[HTML][HTML] The gut-brain connection: Exploring the influence of the gut microbiota on neuroplasticity and neurodevelopmental disorders

F Damiani, S Cornuti, P Tognini - Neuropharmacology, 2023 - Elsevier
Neuroplasticity refers to the ability of brain circuits to reorganize and change the properties
of the network, resulting in alterations in brain function and behavior. It is traditionally …

Glucocorticoids orchestrate adult hippocampal plasticity: growth points and translational aspects

NV Gulyaeva - Biochemistry (Moscow), 2023 - Springer
The review analyzes modern concepts about the control of various mechanisms of the
hippocampal neuroplasticity in adult mammals and humans by glucocorticoids …

Carnosic acid mitigates depression-like behavior in ovariectomized mice via activation of Nrf2/HO-1 pathway

DM Samy, DK Mostafa, SR Saleh, PS Hassaan… - Molecular …, 2023 - Springer
The peri-and post-menopausal periods have been described as the “window of
vulnerability” for the development of depressive symptoms that impair women activities and …

Biomarkers of ketamine's antidepressant effect: An umbrella review

S Meshkat, RC Ho, B Cao, KM Teopiz… - Journal of Affective …, 2023 - Elsevier
Ketamine is a NMDA receptor antagonist that has a rapid acting antidepressant effect with
high efficacy in treatment-resistant patients. Ketamine is a beneficial antidepressant for …

Selective PPAR-Delta/PPAR-gamma activation improves cognition in a model of Alzheimer's disease

I Steinke, M Govindarajulu, PD Pinky, J Bloemer, S Yoo… - Cells, 2023 - mdpi.com
Background: The continuously increasing association of Alzheimer's disease (AD) with
increased mortality rates indicates an unmet medical need and the critical need for …

Neurotrophic effects of intermittent fasting, calorie restriction and exercise: a review and annotated bibliography

E Mayor - Frontiers in Aging, 2023 - frontiersin.org
In the last decades, important progress has been achieved in the understanding of the
neurotrophic effects of intermittent fasting (IF), calorie restriction (CR) and exercise …

Role of long noncoding RNAs; BDNF-AS and 17A and their relation to GABAergic dysfunction in Egyptian epileptic patients

AA Zayed, MM Seleem, HA Darwish… - Metabolic Brain …, 2023 - Springer
Epilepsy is a chronic neurological disorder characterized by recurrent unprovoked seizures.
Lately, long noncoding RNAs (lncRNAs) have been increasingly appreciated as regulators …

Protective Effect of Dexmedetomidine against Hyperoxia-Damaged Cerebellar Neurodevelopment in the Juvenile Rat

R Puls, C von Haefen, C Bührer, S Endesfelder - Antioxidants, 2023 - mdpi.com
Impaired cerebellar development of premature infants and the associated impairment of
cerebellar functions in cognitive development could be crucial factors for …

Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling

MA Minaya, S Mahali, AK Iyer, AM Eteleeb… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: More than 50 mutations in the MAPT gene result in heterogeneous forms of
frontotemporal lobar dementia with tau inclusions (FTLD-Tau). However, early pathogenic …

Dietary flavonoids-rich Citrus reticulata peel extract interacts with CREB signaling to suppress seizures and linked neurobehavioral impairments in a kindling mouse …

P Sharma, P Dhiman, D Singh - Nutritional Neuroscience, 2023 - Taylor & Francis
Objectives: The citrus fruits peel contains a variety of bioactive metabolites that have shown
multiple therapeutic effects. However, despite having substantial ethnomedicinal value …