Ponatinib: An update on its drug targets, therapeutic potential and safety
Y Gao, Y Ding, X Tai, C Zhang, D Wang - Biochimica et Biophysica Acta …, 2023 - Elsevier
Leukemia is a malignancy of the hematopoietic system, and as its pathogenesis has
become better understood, three generations of tyrosine kinase inhibitors (TKIs) have been …
become better understood, three generations of tyrosine kinase inhibitors (TKIs) have been …
Targeting the RET tyrosine kinase in neuroblastoma: a review and application of a novel selective drug design strategy
EA Steen, M Basilaia, W Kim, T Getz… - Biochemical …, 2023 - Elsevier
Abstract The RET (REarranged during T ransfection) gene, which encodes for a
transmembrane receptor tyrosine kinase, is an established oncogene associated with the …
transmembrane receptor tyrosine kinase, is an established oncogene associated with the …
Enhancing longitudinal monitoring of neuroblastoma in commonly applied pre-clinical mouse models
SMR Rahavi - 2023 - open.library.ubc.ca
Neuroblastoma (NB), a complex pediatric cancer primarily affecting the adrenal medulla and
paraspinal sympathetic ganglia, presents significant clinical challenges due to its …
paraspinal sympathetic ganglia, presents significant clinical challenges due to its …