Inflammation and gut dysbiosis as drivers of CKD–MBD

P Evenepoel, P Stenvinkel, C Shanahan… - Nature Reviews …, 2023 - nature.com
Abstract Two decades ago, Kidney Disease: Improving Global Outcomes coined the term
chronic kidney disease–mineral and bone disorder (CKD–MBD) to describe the syndrome of …

Vascular calcification in CKD: New insights into its mechanisms

N Ding, Y Lv, H Su, Z Wang, X Kong… - Journal of Cellular …, 2023 - Wiley Online Library
Vascular calcification (VC) is a common complication of chronic kidney disease (CKD) and
contributes to an increased risk of cardiovascular morbidity and mortality. However, effective …

Quantitative proteomics analysis of COVID-19 patients: Fetuin-A and tetranectin as potential modulators of innate immune responses

B Alghanem, FA Mansour, H Shaibah, K Almuhalhil… - Heliyon, 2023 - cell.com
Abstract Treatment of severe cases of coronavirus disease 2019 (COVID-19) is extremely
important to minimize death and end-organ damage. Here we performed a proteomic …

Can we reverse arterial stiffness by intervening on CKD-MBD biomarkers?

MG Vervloet - Clinical Kidney Journal, 2023 - academic.oup.com
The increased cardiovascular risk of chronic kidney disease may in part be the
consequence of arterial stiffness, a typical feature of kidney failure. Deranged homeostasis …

Future treatment of vascular calcification in chronic kidney disease

M Cozzolino, F Maffei Faccioli, A Cara… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Cardiovascular disease (CVD) is one of the global leading causes of morbidity
and mortality in chronic kidney disease (CKD) patients. Vascular calcification (VC) is a major …

[HTML][HTML] Emerging evidence linking the liver to the cardiovascular system: Liver-derived secretory factors

X Liu, Y Shao, L Han, R Zhang… - Journal of clinical and …, 2023 - ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality
worldwide. Recently, accumulating evidence has revealed hepatic mediators, termed as …

[HTML][HTML] Humoral and cellular factors inhibit phosphate-induced vascular calcification during the growth period

Y Kamei, Y Okumura, Y Adachi, Y Mori… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Hyperphosphatemia is an independent and non-classical risk factor of cardiovascular
disease and mortality in patients with chronic kidney disease (CKD). Increased levels of …

[HTML][HTML] Reconsidering the role of albumin towards amorphous calcium phosphate-based calciprotein particles formation and stability from a physico-chemical …

R Gelli, F Ridi - Colloids and Surfaces B: Biointerfaces, 2023 - Elsevier
The formation of calciprotein particles (CPPs) in serum is a physiological phenomenon
fundamental to prevent the rise of ectopic calcifications. CPPs are colloidal hybrid particles …

Disorders of bone mineral metabolism in chronic kidney disease

CP Schmitt, RC Shroff - Pediatric Kidney Disease, 2023 - Springer
In children with chronic kidney disease (CKD) optimal control of bone and mineral
homeostasis is essential not only for the prevention of debilitating skeletal complications and …

骨标志物与维持性血液透析患者冠状动脉钙化的关系探讨

周丽娜, 董芍芍, 章圣泽, 王牡丹, 朱源, 黄文 - 中国血液净化, 2023 - cjbp.org.cn
目的探讨骨标志物与维持性血液透析(maintenance hemodialysis, MHD) 患者冠状动脉钙化(
coronary artery calcification, CAC) 的关系, 探讨骨标志物的可能影响因素. 方法选取温州市人民 …