The complex molecular pharmacology of the dopamine D2 receptor: Implications for pramipexole, ropinirole, and rotigotine
M Ferraiolo, E Hermans - Pharmacology & therapeutics, 2023 - Elsevier
With L-DOPA, dopamine agonists such as pramipexole, ropinirole and rotigotine constitute
key therapeutic options for the management of motor symptoms of Parkinson's disease …
key therapeutic options for the management of motor symptoms of Parkinson's disease …
Kinase Activity Is Not Required for G Protein–Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development
J Gerhards, LD Maerz, ESF Matthees… - Journal of the …, 2023 - journals.lww.com
Background G protein–coupled receptor kinase 4 (GRK4) is considered a central regulator
of blood pressure through phosphorylation of renal dopaminergic receptors and subsequent …
of blood pressure through phosphorylation of renal dopaminergic receptors and subsequent …
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of …
M Sánchez-Soto, NM Boldizsar, KA Schardien… - Biomolecules, 2023 - mdpi.com
The D2 dopamine receptor (D2R) signals through both G proteins and β-arrestins to
regulate important physiological processes, such as movement, reward circuitry, emotion …
regulate important physiological processes, such as movement, reward circuitry, emotion …
Design and Synthesis of Substituted N, 3, 3-Triphenylpropanamide and 1-Benzhydryl-N-phenylazetidine-3-carboxamide Analogs and their Biological Evaluation
M Dorogan - 2023 - academicworks.cuny.edu
As D 1 R agonism has significant implications in the treatment of cognitive deficits, we
sought to develop novel D 1 R PAMs, through the derigidification of BMS D 1 R PAM hit …
sought to develop novel D 1 R PAMs, through the derigidification of BMS D 1 R PAM hit …
[PDF][PDF] The role of G-proteins and G-protein-coupledreceptors in human disease
YC Xian - MedScien, 2023 - deanfrancispress.com
In human diseases associated with G protein, changes in abnormal content and distribution
of multiple signalingmolecules and abnormal signaling pathways play critical roles in …
of multiple signalingmolecules and abnormal signaling pathways play critical roles in …
[PDF][PDF] ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ НАУЧНОЕ УЧРЕЖДЕНИЕ" НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИНСТИТУТ КЛИНИЧЕСКОЙ И …
КИЭ РЕВМАТОЛОГИИ - МОсква, 2023 - rheumatolog.su
Untitled Page 1 Page 2 ОрганизатОр кОнференции: ФЕДЕРАЛЬНОЕ
ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ НАУЧНОЕ УЧРЕЖДЕНИЕ «НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ …
ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ НАУЧНОЕ УЧРЕЖДЕНИЕ «НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ …