[HTML][HTML] A Comprehensive Review on the Roles of Metals Mediating Insect–Microbial Pathogen Interactions

S Khan, M Lang - Metabolites, 2023 - mdpi.com
Insects and microbial pathogens are ubiquitous and play significant roles in various
biological processes, while microbial pathogens are microscopic organisms that can cause …

Mycobacterial phosphodiesterase Rv0805 is a virulence determinant and its cyclic nucleotide hydrolytic activity is required for propionate detoxification

JR McDowell, G Bai, E Lasek‐Nesselquist… - Molecular …, 2023 - Wiley Online Library
Cyclic AMP (cAMP) signaling is essential to Mycobacterium tuberculosis (Mtb)
pathogenesis. However, the roles of phosphodiesterases (PDEs) Rv0805, and the recently …

[HTML][HTML] Genomic Insights into Bacterial Resistance to Proline-Rich Antimicrobial Peptide Bac7

PV Panteleev, VN Safronova, RN Kruglikov, IA Bolosov… - Membranes, 2023 - mdpi.com
Proline-rich antimicrobial peptides (PrAMPs) having a potent antimicrobial activity and a
modest toxicity toward mammalian cells attract much attention as new templates for the …

[HTML][HTML] The PDIM paradox of Mycobacterium tuberculosis: new solutions to a persistent problem

CV Mulholland, TJ Wiggins, J Cui, C Vilcheze… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Phthiocerol dimycocerosate (PDIM) is an essential virulence lipid of Mycobacterium
tuberculosis. In vitro culturing rapidly selects for spontaneous mutations that cause PDIM …

Organohalide respiration by a Desulforhopalus-dominated community

C Zhang, S Atashgahi, TNP Bosma, H Smidt - bioRxiv, 2023 - biorxiv.org
Despite the fact that several potential organohalide-respiring bacteria (OHRB) were
discovered in metagenome-assembled genomes (MAGs) in our previous study of marine …

Mycobacterium tuberculosis employs atypical and different classes of B12 switches to control separate operons

T Kipkorir, P Polgar, D Barker, A D'Halluin, Z Patel… - bioRxiv, 2023 - biorxiv.org
Abstract Vitamin B12 (B12), an essential cofactor in all domains of life, is produced de novo
by only a small subset of prokaryotes, but B12-sensing riboswitches are some of the most …

A brief report on the of mycobacterial proteins regulated by the loss of PtkA in Mtb-H37Ra

KK Srivastava, S Jaiswal - bioRxiv, 2023 - biorxiv.org
Kinase-phosphatase signaling plays an important role in cellular signaling pathways. The
genome of Mycobacterium tuberculosis,(the causative agent of tuberculosis), is embossed …

Dependency on the host vitamin B12 has shaped the Mycobacterium tuberculosis Complex evolution

J Gonzalo-Asensio, E Campos-Pardos, S Uranga - 2023 - researchsquare.com
Human and animal tuberculosis is caused by the Mycobacterium tuberculosis Complex,
which have evolved a genomic decay of cobalamin (vitamin B12) biosynthetic genes …