[HTML][HTML] Impact of immunity on coronary artery disease: an updated pathogenic interplay and potential therapeutic strategies

N Laera, P Malerba, G Vacanti, S Nardin, M Pagnesi… - Life, 2023 - mdpi.com
Coronary artery disease (CAD) is the leading cause of death worldwide. It is a result of the
buildup of atherosclerosis within the coronary arteries. The role of the immune system in …

[HTML][HTML] Residual risks and evolving atherosclerotic plaques

SK Noothi, MR Ahmed, DK Agrawal - Molecular and Cellular Biochemistry, 2023 - Springer
Atherosclerotic disease of the coronary and carotid arteries is the primary global cause of
significant mortality and morbidity. The chronic occlusive diseases have changed the …

Neutrophil counts and cardiovascular disease

J Luo, JQ Thomassen, BG Nordestgaard… - European Heart …, 2023 - academic.oup.com
Abstract Background and Aims Anti-inflammatory trials have shown considerable benefits for
cardiovascular disease. High neutrophil counts, an easily accessible inflammation …

Impact of impaired cholesterol homeostasis on neutrophils in atherosclerosis

B Tucker, J Ephraums, TW King, K Abburi… - … and Vascular Biology, 2023 - Am Heart Assoc
Atherosclerosis is complex chronic disease characterized by intimal cholesterol
accumulation and vascular inflammation. There is a well-established relationship of …

Evolving concepts in the pathophysiology of atherosclerosis: From endothelial dysfunction to thrombus formation through multiple shades of inflammation

G Cimmino, S Muscoli, S De Rosa… - Journal of …, 2023 - journals.lww.com
Atherosclerosis is the anatomo-pathological substrate of most cardio, cerebro and vascular
diseases such as acute and chronic coronary syndromes, stroke and peripheral artery …

Antagonistic roles of human platelet integrin αIIbβ3 and chemokines in regulating neutrophil activation and fate on arterial thrombi under flow

C Schönichen, SJ Montague, SLN Brouns… - … and Vascular Biology, 2023 - Am Heart Assoc
Background: Platelets and neutrophils are the first blood cells accumulating at sites of
arterial thrombus formation, and both cell types contribute to the pathology of thrombotic …

Prognostic value of multiple complete blood count-derived indices in intermediate coronary lesions

Y Yang, C Song, L Jia, Q Dong, W Song, D Yin… - Angiology, 2023 - journals.sagepub.com
Complete blood count (CBC)-derived indices have been proposed as reliable inflammatory
biomarkers to predict outcomes in the context of coronary artery disease. These indices …

[HTML][HTML] Worsening thrombotic complication of atherosclerotic plaques due to neutrophils extracellular traps: a systematic review

F Nappi, F Bellomo, SS Avtaar Singh - Biomedicines, 2023 - mdpi.com
Neutrophil extracellular traps (NETs) recently emerged as a newly recognized contributor to
venous and arterial thrombosis. These strands of DNA, extruded by activated or dying …

The neutrophil percentage-to-albumin ratio is associated with all-cause mortality in patients with atrial fibrillation: a retrospective study

Y Xu, Z Lin, C Zhu, D Song, B Wu, K Ji… - Journal of Inflammation …, 2023 - Taylor & Francis
Objective The present study aimed to evaluate the relationship between all-cause mortality
and the neutrophil percentage-to-albumin ratio (NPAR) in patients with atrial fibrillation (AF) …

[HTML][HTML] New insights into pathophysiology and new risk factors for ACS

M Nardin, M Verdoia, N Laera, D Cao… - Journal of Clinical …, 2023 - mdpi.com
Cardiovascular disease still represents the main cause of mortality worldwide. Despite huge
improvements, atherosclerosis persists as the principal pathological condition, both in stable …