[HTML][HTML] The influence of early environment and micronutrient availability on developmental epigenetic programming: lessons from the placenta
R Sainty, MJ Silver, AM Prentice… - Frontiers in Cell and …, 2023 - frontiersin.org
DNA methylation is the most commonly studied epigenetic mark in humans, as it is well
recognised as a stable, heritable mark that can affect genome function and influence gene …
recognised as a stable, heritable mark that can affect genome function and influence gene …
[HTML][HTML] Integration and implementation of precision medicine in the multifaceted inflammatory bowel disease
GSK Jagirdhar, JA Perez, AB Perez… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a complex disease with variability in genetic,
environmental, and lifestyle factors affecting disease presentation and course. Precision …
environmental, and lifestyle factors affecting disease presentation and course. Precision …
[HTML][HTML] Epigenetic inheritance is unfaithful at intermediately methylated CpG sites
AD Hay, NJ Kessler, D Gebert, N Takahashi… - Nature …, 2023 - nature.com
DNA methylation at the CpG dinucleotide is considered a stable epigenetic mark due to its
presumed long-term inheritance through clonal expansion. Here, we perform high …
presumed long-term inheritance through clonal expansion. Here, we perform high …
[HTML][HTML] Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis
Background Choosing the appropriate antipsychotic drug (APD) treatment for patients with
schizophrenia (SCZ) can be challenging, as the treatment response to APD is highly …
schizophrenia (SCZ) can be challenging, as the treatment response to APD is highly …
[HTML][HTML] Selecting a dietary supplement with appropriate dosing for 6 key nutrients in pregnancy
KA Sauder, GL Couzens, RL Bailey, CW Hockett… - The American journal of …, 2023 - Elsevier
Background Most pregnant women in the United States (US) are at risk of inadequate intake
of key nutrients during pregnancy from foods alone. Current dietary supplement practices …
of key nutrients during pregnancy from foods alone. Current dietary supplement practices …
Maternal nutritional status modifies heat-associated growth restriction in women with chronic malnutrition
K Shankar, SA Ali, ML Ruebel, S Jessani… - PNAS …, 2023 - academic.oup.com
Rapid changes in the global climate are deepening existing health disparities from resource
scarcity and malnutrition. Rising ambient temperatures represent an imminent risk to …
scarcity and malnutrition. Rising ambient temperatures represent an imminent risk to …
Development of epigenetic biomarkers in aquatic organisms
D Anastasiadi, A Beemelmanns - Epigenetics in aquaculture, 2023 - Wiley Online Library
Biomarkers, as measurable characteristics of normal or pathogenic processes, are used in
the context of human health and to monitor animal welfare and ecosystem status. Epigenetic …
the context of human health and to monitor animal welfare and ecosystem status. Epigenetic …
[HTML][HTML] Multi-omics approaches for precision obesity management: Potentials and limitations of omics in precision prevention, treatment and risk reduction of obesity
S Woldemariam, TE Dorner, T Wiesinger… - Wiener Klinische …, 2023 - Springer
Introduction Obesity is a multifactorial chronic disease that cannot be addressed by simply
promoting better diets and more physical activity. To date, not a single country has …
promoting better diets and more physical activity. To date, not a single country has …
Identifying Foods that optimize intake of key micronutrients during pregnancy
Background Most pregnant women in the United States are at risk of inadequate intake of
vitamin A, vitamin D, folic acid, calcium, iron, and omega-3 fatty acids from foods alone. Very …
vitamin A, vitamin D, folic acid, calcium, iron, and omega-3 fatty acids from foods alone. Very …
Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders
BM Levasseur, EE Young, JA Christianson - Visceral Pain, 2023 - Springer
Exposure to adversity or stress during early development increases the likelihood of
developing chronic pain disorders, as well as comorbid mood disorders, later in life. Early …
developing chronic pain disorders, as well as comorbid mood disorders, later in life. Early …