[HTML][HTML] The influence of early environment and micronutrient availability on developmental epigenetic programming: lessons from the placenta

R Sainty, MJ Silver, AM Prentice… - Frontiers in Cell and …, 2023 - frontiersin.org
DNA methylation is the most commonly studied epigenetic mark in humans, as it is well
recognised as a stable, heritable mark that can affect genome function and influence gene …

[HTML][HTML] Integration and implementation of precision medicine in the multifaceted inflammatory bowel disease

GSK Jagirdhar, JA Perez, AB Perez… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a complex disease with variability in genetic,
environmental, and lifestyle factors affecting disease presentation and course. Precision …

[HTML][HTML] Epigenetic inheritance is unfaithful at intermediately methylated CpG sites

AD Hay, NJ Kessler, D Gebert, N Takahashi… - Nature …, 2023 - nature.com
DNA methylation at the CpG dinucleotide is considered a stable epigenetic mark due to its
presumed long-term inheritance through clonal expansion. Here, we perform high …

[HTML][HTML] Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis

LK Guo, Y Su, YYN Zhang, H Yu, Z Lu, WQ Li… - Military Medical …, 2023 - Springer
Background Choosing the appropriate antipsychotic drug (APD) treatment for patients with
schizophrenia (SCZ) can be challenging, as the treatment response to APD is highly …

[HTML][HTML] Selecting a dietary supplement with appropriate dosing for 6 key nutrients in pregnancy

KA Sauder, GL Couzens, RL Bailey, CW Hockett… - The American journal of …, 2023 - Elsevier
Background Most pregnant women in the United States (US) are at risk of inadequate intake
of key nutrients during pregnancy from foods alone. Current dietary supplement practices …

Maternal nutritional status modifies heat-associated growth restriction in women with chronic malnutrition

K Shankar, SA Ali, ML Ruebel, S Jessani… - PNAS …, 2023 - academic.oup.com
Rapid changes in the global climate are deepening existing health disparities from resource
scarcity and malnutrition. Rising ambient temperatures represent an imminent risk to …

Development of epigenetic biomarkers in aquatic organisms

D Anastasiadi, A Beemelmanns - Epigenetics in aquaculture, 2023 - Wiley Online Library
Biomarkers, as measurable characteristics of normal or pathogenic processes, are used in
the context of human health and to monitor animal welfare and ecosystem status. Epigenetic …

[HTML][HTML] Multi-omics approaches for precision obesity management: Potentials and limitations of omics in precision prevention, treatment and risk reduction of obesity

S Woldemariam, TE Dorner, T Wiesinger… - Wiener Klinische …, 2023 - Springer
Introduction Obesity is a multifactorial chronic disease that cannot be addressed by simply
promoting better diets and more physical activity. To date, not a single country has …

Identifying Foods that optimize intake of key micronutrients during pregnancy

KA Sauder, CC Cohen, NT Mueller, CW Hockett… - The Journal of …, 2023 - Elsevier
Background Most pregnant women in the United States are at risk of inadequate intake of
vitamin A, vitamin D, folic acid, calcium, iron, and omega-3 fatty acids from foods alone. Very …

Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders

BM Levasseur, EE Young, JA Christianson - Visceral Pain, 2023 - Springer
Exposure to adversity or stress during early development increases the likelihood of
developing chronic pain disorders, as well as comorbid mood disorders, later in life. Early …