Chimeric antigen receptor (CAR)-T cells have demonstrated significant improvements in the
treatment of refractory B-cell malignancies that previously showed limited survival. In …

Novel unconventional radiotherapy techniques: Current status and future perspectives –
Report from the 2nd international radiation oncology online seminar - ScienceDirect Skip to …

Poor intratumoral infiltration is the major challenge for chimeric antigen receptor (CAR)-T
cell therapy in solid tumors. Hypofractionated radiotherapy (HFRT) has been reported to …

Ionizing radiation (IR) is used to treat 50% of cancers. While the cytotoxic effects related to
DNA damage with IR have been known since the early 20th century, the role of the immune …

Although the “abscopal phenomenon” has been described several decades ago, this
phenomenon lately has been obtaining momentous traction with the dawn of immune …

Immune checkpoint inhibitors (ICIs) have revolutionized the current treatment landscape for
cancer, yet the response rates of ICIs remain unmet. Synergistic with immunotherapy, low …

Objective To investigate the role of consolidative thoracic radiation (TRT) in extensive-stage
small-cell lung cancer (ES-SCLC) receiving first-line chemo-immunotherapy followed by …

Patients with chemo-refractory metastatic colorectal cancer (mCRC) have poor prognoses.
The application of programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 …

Introduction Immune-checkpoint inhibitors (IO) have significantly improved outcomes of
patients with non-oncogene-addicted non-small cell lung cancer (NSCLC), becoming the …

Radiotherapy has unique immunostimulatory and immunosuppressive effects. Although
high-dose radiotherapy has been found to have systemic antitumor effects, clinically …