Radiotherapy as a means to increase the efficacy of T-cell therapy in solid tumors
PA Laurent, D Morel, L Meziani, S Depil… - …, 2023 - Taylor & Francis
Chimeric antigen receptor (CAR)-T cells have demonstrated significant improvements in the
treatment of refractory B-cell malignancies that previously showed limited survival. In …
treatment of refractory B-cell malignancies that previously showed limited survival. In …
[HTML][HTML] Novel unconventional radiotherapy techniques: Current status and future perspectives–Report from the 2nd international radiation oncology online seminar
S Tubin, MC Vozenin, Y Prezado, M Durante… - Clinical and …, 2023 - Elsevier
Novel unconventional radiotherapy techniques: Current status and future perspectives –
Report from the 2nd international radiation oncology online seminar - ScienceDirect Skip to …
Report from the 2nd international radiation oncology online seminar - ScienceDirect Skip to …
[HTML][HTML] Optimized CAR-T therapy based on spatiotemporal changes and chemotactic mechanisms of MDSCs induced by hypofractionated radiotherapy
B Zhang, M Hu, Q Ma, K Li, X Li, X He, P Shu, Y Chen… - Molecular Therapy, 2023 - cell.com
Poor intratumoral infiltration is the major challenge for chimeric antigen receptor (CAR)-T
cell therapy in solid tumors. Hypofractionated radiotherapy (HFRT) has been reported to …
cell therapy in solid tumors. Hypofractionated radiotherapy (HFRT) has been reported to …
[HTML][HTML] Harnessing the immunological effects of radiation to improve immunotherapies in cancer
Ionizing radiation (IR) is used to treat 50% of cancers. While the cytotoxic effects related to
DNA damage with IR have been known since the early 20th century, the role of the immune …
DNA damage with IR have been known since the early 20th century, the role of the immune …
On target methods to induce abscopal phenomenon for Off‐Target effects: From happenstance to happenings
BE Nelson, JJ Adashek, SH Lin, V Subbiah - Cancer medicine, 2023 - Wiley Online Library
Although the “abscopal phenomenon” has been described several decades ago, this
phenomenon lately has been obtaining momentous traction with the dawn of immune …
phenomenon lately has been obtaining momentous traction with the dawn of immune …
Exploring low-dose radiotherapy to overcome radio-immunotherapy resistance
J Wang, J Zhang, W Wen, F Wang, M Wu… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Immune checkpoint inhibitors (ICIs) have revolutionized the current treatment landscape for
cancer, yet the response rates of ICIs remain unmet. Synergistic with immunotherapy, low …
cancer, yet the response rates of ICIs remain unmet. Synergistic with immunotherapy, low …
[HTML][HTML] Role of consolidative thoracic radiation in extensive-stage small-cell lung cancer with first-line chemoimmunotherapy: a retrospective study from a single …
Y Li, W Jing, X Jing, Y Sun, X Tang, J Guo, Y Zhang… - Discover Oncology, 2023 - Springer
Objective To investigate the role of consolidative thoracic radiation (TRT) in extensive-stage
small-cell lung cancer (ES-SCLC) receiving first-line chemo-immunotherapy followed by …
small-cell lung cancer (ES-SCLC) receiving first-line chemo-immunotherapy followed by …
[HTML][HTML] PD-1 inhibitor combined with radiotherapy and GM-CSF in MSS/pMMR metastatic colon cancer: a case report
J Yang, P Xing, Y Kong, M Xu, L Zhang - Frontiers in Oncology, 2023 - frontiersin.org
Patients with chemo-refractory metastatic colorectal cancer (mCRC) have poor prognoses.
The application of programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 …
The application of programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 …
What to do after immune-checkpoint inhibitors failure in advanced non-small cell lung cancer: an expert opinion and review
AG Agostara, L Roazzi, F Villa, R Romano'… - Expert Review of …, 2023 - Taylor & Francis
Introduction Immune-checkpoint inhibitors (IO) have significantly improved outcomes of
patients with non-oncogene-addicted non-small cell lung cancer (NSCLC), becoming the …
patients with non-oncogene-addicted non-small cell lung cancer (NSCLC), becoming the …
Low-dose radiation therapy mobilizes antitumor immunity: New findings and future perspectives.
L Zhou, Y Liu, Y Wu, X Yang, SK FM, Y Lu… - International Journal of …, 2023 - europepmc.org
Radiotherapy has unique immunostimulatory and immunosuppressive effects. Although
high-dose radiotherapy has been found to have systemic antitumor effects, clinically …
high-dose radiotherapy has been found to have systemic antitumor effects, clinically …