Orientation of the dysferlin c2a domain is responsive to the composition of lipid membranes

AP Carpenter, P Khuu, T Weidner… - The Journal of …, 2023 - ACS Publications
Dysferlin is a 230 kD protein that plays a critical function in the active resealing of micron-
sized injuries to the muscle sarcolemma by recruiting vesicles to patch the injured site via …

Novel five nucleotide deletion in dysferlin leads to autosomal recessive limb‐girdle muscular dystrophy

YL Chen, WB Wu, P Wang, PK Yip, YN Wu… - Physiological …, 2023 - Wiley Online Library
Muscular dystrophy (MD) is a genetic disorder that causes progressive muscle weakness
and degeneration. Limb‐girdle muscular dystrophy (LGMD) is a type of MD that mainly …

Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle Cells and Binds to Dysferlin and Myoferlin

T Fontelonga, AJ Hall, JL Brown, YL Jung… - Advanced …, 2023 - Wiley Online Library
Tetraspanins organize protein complexes at the cell membrane and are responsible for
assembling diverse binding partners in changing cellular states. Tetraspanin CD82 is a …

Contributions of individual satellite cells to muscle regeneration assessed using a confetti mouse model

H Heemskerk, NS Jagannathan, NJM Nasir… - bioRxiv, 2023 - biorxiv.org
Insufficient regeneration is implicated in muscle pathologies, but much remains unknown
about the regenerative output of individual muscle stem cells, called satellite cells (SCs) …

Function and biomechanics of dysferlin-deficient skeletal muscle

E Lloyd - 2023 - research-repository.uwa.edu.au
Dysferlinopathies are a group of muscular dystrophies caused by genetic deficiency of the
protein dysferlin. Manifesting post-growth, the disease is characterised by progressive …