The pharmacological treatment of cancer-related pain is unsatisfactory. Tetrodotoxin (TTX)
has shown analgesia in preclinical models and clinical trials, but its clinical efficacy and …

To improve currently available cancer treatments, nanomaterials are employed as smart
drug delivery vehicles that can be engineered to locally target cancer cells and respond to …

Importance Chemotherapy-induced peripheral neuropathy (CIPN), one of the most common
and severe adverse effects of chemotherapy, is associated with worse quality of life among …

Opioids are employed in the management of chemotherapy-induced neuropathic pain
(CINP) when other pain management approaches have failed and proven ineffective …

Although the immunotherapy advent has revolutionized cancer treatment, it, unfortunately,
does not spare cancer patients from possible immune-related adverse events (irAEs), which …

Introduction Duloxetine has previously been reported to be promising in the setting of
chemotherapy-induced peripheral neuropathy (CIPN). The aim of this study was to conduct …

Abstract Alterations in calcium (Ca 2+) signaling is a major mechanism in the development
of chemotherapy-induced peripheral neuropathy (CIPN), a side effect caused by multiple …

Neuropathic pain is caused by the lesion or disease of the somatosensory system and can
be initiated and/or maintained by both central and peripheral mechanisms. Nerve injury …

The incidence of breast cancer in China was 19.2% in 2018, with a five-year survival rate of
up to 80%. The impairments that may result from breast cancer treatment, such as …

Purpose This review provides an assessment of psychological distress (depressive
symptoms and anxiety symptoms) and the impact on quality of life in breast cancer survivors …