Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of upper and lower
motor neurons (MNs) leading to paralysis and, ultimately, death by respiratory failure 3–5 …

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are severely
debilitating and progressive neurodegenerative disorders. A distinctive pathological feature …

Abstract Introduction/Aims Higher urate levels are associated with improved ALS survival in
retrospective studies, however whether raising urate levels confers a survival advantage is …

Amyotrophic lateral sclerosis is a relentless neurodegenerative disease that is mostly fatal
within 3–5 years and is diagnosed on evidence of progressive upper and lower motor …

Introduction Amyotrophic lateral sclerosis (ALS) is a rare, devastating neurodegenerative
disease that affects upper and lower motor neurons. To date, no effective treatment or …

The MUNIX technique allows us to estimate the number and size of surviving motor units
(MUs). Previous studies on ALS found correlations between MUNIX and several clinical …

Objective To investigate the relationship between serum uric acid (UA) and survival in
sporadic amyotrophic lateral sclerosis (sALS) patients. Method A total of 801 sporadic …

Background: Currently, there is no effective treatment for amyotrophic lateral sclerosis (ALS),
a devastating neurodegenerative disorder. Many biomarkers have been proposed, but …

Background: ALS is a neurodegenerative disorder characterised by the death of motor
neurons (MNs) in the brain stem and spinal cord. The most common genetic mutation …

Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive disease resulting in the
death of the upper and lower motor neurons, around 15% of those with ALS also have …