[HTML][HTML] Receptor-mediated drug delivery of bispecific therapeutic antibodies through the blood-brain barrier

WM Pardridge - Frontiers in drug delivery, 2023 - frontiersin.org
Therapeutic antibody drug development is a rapidly growing sector of the pharmaceutical
industry. However, antibody drug development for the brain is a technical challenge, and …

[HTML][HTML] Treatment of Parkinson's disease with biologics that penetrate the blood–brain barrier via receptor-mediated transport

WM Pardridge - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Parkinson's disease (PD) is characterized by neurodegeneration of nigral-striatal neurons in
parallel with the formation of intra-neuronal α-synuclein aggregates, and these processes …

[HTML][HTML] Neurotrophic factors in the physiology of motor neurons and their role in the pathobiology and therapeutic approach to amyotrophic lateral sclerosis

WM Stansberry, BA Pierchala - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
The discovery of the neurotrophins and their potent survival and trophic effects led to great
enthusiasm about their therapeutic potential to rescue dying neurons in neurodegenerative …

Exploring the Effects of Cannabidiol on Psychological Health, Cognitive Function, Neural Health, And Natural Killer Cells

A Ramani - 2023 - digscholarship.unco.edu
Abstract Cannabidiol (CBD), a non-psychotropic cannabis sativa derivative, is gaining
attention as a potential promotor of neurological function and cognitive health and as a …

[PDF][PDF] Transplantation of mesenchymal stem cells in ALS. PROGRESS IN BRAIN RESEARCH. 201 pp: 333-359.

L Mazzini, A Vercelli, F Ivana, M Boido, R Cantello… - 2023 - iris.unito.it
Abstract Amyotrophic Lateral Sclerosis (ALS) is a devastating incurable neurodegenerative
disease that targets motor neurons (MNs) in the primary motor cortex, brainstem and spinal …