Neoadjuvant immunotherapy: a promising new standard of care

E Boydell, JL Sandoval, O Michielin, M Obeid… - International Journal of …, 2023 - mdpi.com
Neoadjuvant immunotherapy has emerged as a promising approach in the treatment of
various malignancies, with preclinical studies showing improved immune responses in the …

Perspectives on the future of urothelial carcinoma therapy: chemotherapy and beyond

A Bianchi, M von Deimling, M Pallauf… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Despite recent developments in the landscape of urothelial carcinoma (UC)
treatment, platinum combination chemotherapy still remains a milestone. Recently …

Glabridin inhibits urothelial bladder carcinoma cell growth in vitro and in vivo by inducing cell apoptosis and cell cycle arrest

Z Yang, Y Bi, W Xu, R Guo, M Hao… - Chemical Biology & …, 2023 - Wiley Online Library
Glabridin (GLA) has a variety of biological activities and therapeutic effects in cancers.
Whereas the effect of GLA on urothelial bladder carcinoma (UBC) cells and its underlying …

FAM111B Acts as an Oncogene in Bladder Cancer

N Huang, L Peng, J Yang, J Li, S Zhang, M Sun - Cancers, 2023 - mdpi.com
Simple Summary Bladder cancer can be categorized into non-muscle-and muscle-invasive
bladder cancer based on the extent of invasion. While non-muscle-invasive bladder cancer …

[HTML][HTML] Impact of rural residence on the presentation, management and survival of patients with non-metastatic muscle-invasive bladder carcinoma

F Dursun, A Elshabrawy, H Wang… - … and Clinical Urology, 2023 - ncbi.nlm.nih.gov
Purpose To assess the impact of rural and remote residence on the receipt of guidelines-
recommended treatment, quality of treatment and overall survival (OS) in patients with non …

Identification of novel lactate metabolism-related lncRNAs with prognostic value for bladder cancer

X Wang, J Pan, Q Guan, N Ren, P Wang… - Frontiers in …, 2023 - frontiersin.org
Background: Bladder cancer (BCA) has high recurrence and metastasis rates, and current
treatment options show limited efficacy and significant adverse effects. It is crucial to find …

Phase II study of neoadjuvant chemotherapy with four cycles of dose‐dense MVAC followed by radical cystectomy in Korean patients with muscle‐invasive or locally …

K Park, HJ Lee, TU Kim, H Ryu, YK Ki… - Asia‐Pacific Journal …, 2023 - Wiley Online Library
Purpose While previous retrospective or phase II studies in Western populations showed
that dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) as …

Predictive signature of response to neoadjuvant chemotherapy in muscle-invasive bladder cancer integrating mRNA expression, taxonomic subtypes, and …

A Font, M Domenech, JL Ramirez, M Marqués… - Frontiers in …, 2023 - frontiersin.org
Background and objective Neoadjuvant chemotherapy (NAC) followed by cystectomy is the
standard of care in muscle-invasive bladder cancer (MIBC). Pathological response has been …

Evaluation of proteolytic activity and serine proteases distribution in plasma from patients with bladder cancer

T Synelnyk, T Vovk, T Halenova, V Tytarenko… - Frontiers in …, 2023 - frontiersin.org
Background Bladder cancer (BC) is an aggressive disease with a poor prognosis. A bladder
tumor, like other malignant neoplasms, is characterized by the presence of both cancer cells …

[HTML][HTML] Targeting the anaphase-promoting complex/cyclosome (APC/C) enhanced antiproliferative and apoptotic response in bladder cancer

HS Nalkiran, DA Yildiz, F Saydam, AI Guzel… - Saudi journal of …, 2023 - Elsevier
Improving the chemotherapy sensitivity of bladder cancer is a current clinical challenge. It is
critical to seek out effective combination therapies that include low doses of cisplatin due to …