Duchenne muscular dystrophy: Disease mechanism and therapeutic strategies

A Bez Batti Angulski, N Hosny, H Cohen… - Frontiers in …, 2023 - frontiersin.org
Duchenne muscular dystrophy (DMD) is a severe, progressive, and ultimately fatal disease
of skeletal muscle wasting, respiratory insufficiency, and cardiomyopathy. The identification …

[HTML][HTML] Muscle: to the neuromuscular disease phenotype in spinal muscular atrophy

NN Jha, JK Kim, YR Her, UR Monani - JCI Insight, 2023 - Am Soc Clin Investig
Spinal muscular atrophy (SMA) is a pediatric-onset neuromuscular disorder caused by
insufficient survival motor neuron (SMN) protein. SMN restorative therapies are now …

A MSTNDel273C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia

MM Chen, Y Zhao, XL Xu, XS Zhang, JL Zhang, SJ Wu… - bioRxiv, 2023 - biorxiv.org
Mutations in the well-known Myostatin (MSTN) produce a “double-muscle” phenotype, which
makes it commercially invaluable for improving livestock meat production and providing high …

MSTN-edited born calves obtained by precision breeding, using CRISPR/Cas9 and SCNT

M Suvá, JI Baston, E Wiedenmann, V Arnold… - 2023 - researchsquare.com
MSTN-edited born calves obtained by precision breeding, using CRISPR/Cas9 and SCNT |
Research Square Research Square Browse Preprints COVID-19 Preprints Protocols Videos …

[PDF][PDF] Please let us know how this document benefits you.

VM Saraswathy, L Zhou, AR McAdow, B Burris… - digitalcommons.wustl.edu
Intrinsic and extrinsic inhibition of neuronal regeneration obstruct spinal cord (SC) repair in
mammals. In contrast, adult zebrafish achieve functional recovery after complete SC …

[HTML][HTML] Muscle: an independent contributor to the neuromuscular spinal muscular atrophy disease phenotype

NN Jha, JK Kim, YR Her, UR Monani - JCI insight, 2023 - ncbi.nlm.nih.gov
Spinal muscular atrophy (SMA) is a pediatric-onset neuromuscular disorder caused by
insufficient survival motor neuron (SMN) protein. SMN restorative therapies are now …