Q fever immunology: the quest for a safe and effective vaccine
Q fever is an infectious zoonotic disease, caused by the Gram-negative bacterium Coxiella
burnetii. Transmission occurs from livestock to humans through inhalation of a survival form …
burnetii. Transmission occurs from livestock to humans through inhalation of a survival form …
B cell receptor (BCR) endocytosis
AD Roberts, JW Taraska - Progress in Molecular Biology and Translational …, 2023 - Elsevier
The B cell receptor (BCR) interacts with foreign antigens to mediate B cell activation and
secretion of antibodies. B cell activation begins with initiation of signaling pathways, such as …
secretion of antibodies. B cell activation begins with initiation of signaling pathways, such as …
Antigen footprint governs activation of the B cell receptor
Antigen binding by B cell receptors (BCR) on cognate B cells elicits a response that
eventually leads to production of antibodies. However, it is unclear what the distribution of …
eventually leads to production of antibodies. However, it is unclear what the distribution of …
Effect of Antigen Valency on Autoreactive B-Cell Targeting
MJ van Weijsten, KR Venrooij, L Lelieveldt… - Molecular …, 2023 - ACS Publications
Many autoimmune diseases are characterized by B cells that mistakenly recognize
autoantigens and produce antibodies toward self-proteins. Current therapies aim to …
autoantigens and produce antibodies toward self-proteins. Current therapies aim to …
Antigen Geometry Tunes Mast Cell Signaling Through Distinct FcϵRI Aggregation and Structural Changes
DA Rinaldi, WK Kanagy, HC Kaye, RM Grattan… - bioRxiv, 2023 - biorxiv.org
Immunoreceptor tyrosine-based activation motif (ITAM)-containing Fc receptors are critical
components of the innate and adaptive immune systems. FcϵRI mediates the allergic …
components of the innate and adaptive immune systems. FcϵRI mediates the allergic …
[HTML][HTML] Antigen Geometry Tunes Mast Cell Signaling Through Distinct FcεRI Aggregation and Structural Changes
DA Rinaldi, WK Kanagy, HC Kaye, RM Grattan… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Immunoreceptor tyrosine-based activation motif (ITAM)-containing Fc receptors are critical
components of the innate and adaptive immune systems. FcεRI mediates the allergic …
components of the innate and adaptive immune systems. FcεRI mediates the allergic …
[HTML][HTML] Interaction of b-cell receptors and antigens with different spatial arrangement
VY Talayev, MV Svetlova, IY Zaichenko… - Russian Journal of …, 2023 - iimmun.ru
B-cell receptors can interact with antigen epitopes on various objects: macromolecules,
microorganisms or on the surface of other cells, eg, follicular dendritic cells. Accordingly, B …
microorganisms or on the surface of other cells, eg, follicular dendritic cells. Accordingly, B …
Class-specific sensing of HIV-1 antigens by the B cell antigen receptor depends on the CH1 domain
Y Ortiz, K Anasti, AK Pane, K Cronin, SM Alam, M Reth - bioRxiv, 2023 - biorxiv.org
How different classes of the B cell antigen receptor (BCR) sense viral antigens used in
vaccination protocols is poorly understood. Here we study antigen binding and sensing of …
vaccination protocols is poorly understood. Here we study antigen binding and sensing of …
[图书][B] Investigating the mechanism of ARPC5/L driven lymph node retention of malignant B cells in Mantle Cell Lymphoma
MN Abdullah - 2023 - search.proquest.com
The immune system is a complex network that can roughly be divided into innate and
adaptive immunity. This system consists of blood cells (hematopoietic) which are able to …
adaptive immunity. This system consists of blood cells (hematopoietic) which are able to …