Enzyme Databases in the Era of Omics and Artificial Intelligence

U Prešern, M Goličnik - International Journal of Molecular Sciences, 2023 - mdpi.com
Enzyme research is important for the development of various scientific fields such as
medicine and biotechnology. Enzyme databases facilitate this research by providing a wide …

[HTML][HTML] ChatGPT usage in the Reactome curation process

K Tiwari, L Matthews, B May, V Shamovsky… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Appreciating the rapid advancement and ubiquity of generative AI, particularly ChatGPT, a
chatbot using large language models like GPT, we endeavour to explore the potential …

Pathway-based, reaction-specific annotation of disease variants for elucidation of molecular phenotypes

M Orlic-Milacic, K Rothfels, L Matthews, A Wright… - Database, 2023 - academic.oup.com
Germline and somatic mutations can give rise to proteins with altered activity, including both
gain and loss-of-function. The effects of these variants can be captured in disease-specific …