Epithelial transport is a multifaceted process crucial for maintaining normal physiological
functions in the human body. This comprehensive review delves into the pathophysiological …

Background: Chemotherapy, as well as opioid and antiemetic drugs, can contribute to
constipation in oncological patients. This systematic review aims to analyse the potential of …

Abstract Background Irinotecan (CPT-11, Camptosar@) is a first-line drug for metastatic
colorectal cancer. CPT-11-induced diarrhea, which is closely related to the concentrations of …

Rationale: Gustation is important to several biological functions in mammals. However,
chemotherapy drugs often harm taste perception in cancer patients, while the underlying …

Simple Summary Constipation is the third most common symptom in patients receiving
cytotoxic chemotherapy, and it can impact their quality of life. There is no clear definition of …

Clinical oncology has shown outstanding progress improving patient survival due to the
incorporation of new drugs. However, treatment success may be reduced by the emergency …

Objectives While the gastrointestinal symptom cluster (GISC) is common in patients
receiving chemotherapy, limited information is available on its underlying mechanism (s) …

Abstract Pogostemon cablin (Blanco) Benth (PCB), a medicinal and edible homologous
Chinese herb, has a protective effect on the structure and function of intestine. In this study …

Abstract Background 5-Fluorouracil (5-FU) is one of the most commonly prescribed
anticancer agents. However, intestinal mucositis is a well-known adverse event, which limits …

Background: Chemotherapeutic drugs used in cancer treatment often result in
gastrointestinal toxicity, notably diarrhea, impacting patients' quality of life. Complementary …