Mitochondrial properties in skeletal muscle fiber

H Dong, SY Tsai - Cells, 2023 - mdpi.com
Mitochondria are the primary source of energy production and are implicated in a wide
range of biological processes in most eukaryotic cells. Skeletal muscle heavily relies on …

[HTML][HTML] Intermediate filaments in the heart: The dynamic duo of desmin and lamins orchestrates mechanical force transmission

G West, S Sedighi, G Agnetti, P Taimen - Current Opinion in Cell Biology, 2023 - Elsevier
The intermediate filament (IF) cytoskeleton supports cellular structural integrity, particularly
in response to mechanical stress. The most abundant IF proteins in mature cardiomyocytes …

Desmin reorganization by stimuli inducing oxidative stress and electrophiles: role of its single cysteine residue

D Moneo-Corcuera, Á Viedma-Poyatos, K Stamatakis… - Antioxidants, 2023 - mdpi.com
The type III intermediate filament proteins vimentin and GFAP are modulated by oxidants
and electrophiles, mainly through perturbation of their single cysteine residues. Desmin, the …

Dynamics of inflammatory cytokine expression in bovine endometrial cells exposed to cow blood plasma small extracellular vesicles (sEV) may reflect high fertility

P Abeysinghe, N Turner, E Mosaad, J Logan… - Scientific Reports, 2023 - nature.com
Aberrant inflammation in the endometrium impairs reproduction and leads to poor fertility.
Small extracellular vesicles (sEV) are nanoparticles 30–200 nm in-size and contain …

Simulated microgravity reduces quality of ovarian follicles and oocytes by disrupting communications of follicle cells

K Cheng, X Feng, C Yang, C Ma, S Niu, L Jia, X Yang… - npj …, 2023 - nature.com
Ovarian follicles are the fundamental structures that support oocyte development, and
communications between oocytes and follicle somatic cells are crucial for oogenesis …

The Mechanoreception in Drosophila melanogaster Oocyte under Modeling Micro- and Hypergravity

IV Ogneva - Cells, 2023 - mdpi.com
The hypothesis about the role of the cortical cytoskeleton as the primary mechanosensor
was tested. Drosophila melanogaster oocytes were exposed to simulated microgravity (by …

Insights into cell-specific functions of microtubules in skeletal muscle development and homeostasis

L Lucas, TA Cooper - International Journal of Molecular Sciences, 2023 - mdpi.com
The contractile cells of skeletal muscles, called myofibers, are elongated multinucleated
syncytia formed and maintained by the fusion of proliferative myoblasts. Human myofibers …

PPARδ activation improves cardiac mitochondrial homeostasis in desmin deficient mice but does not alleviate systolic dysfunction

D Palioura, K Mellidis, K Ioannidou-Kabouri… - Journal of Molecular and …, 2023 - Elsevier
Peroxisome proliferator-activated receptor (PPAR) δ is a major transcriptional regulator of
cardiac energy metabolism with pleiotropic properties, including anti-inflammatory, anti …

[HTML][HTML] Cardiotoxicity as a Possible Side Effect of Statins

A Chaulin - Reviews in Cardiovascular Medicine, 2023 - imrpress.com
According to current views, statins have a wide range of beneficial effects (lipid and non-
lipid) on the cardiovascular system, so they are one of the most commonly used drugs for the …

[HTML][HTML] Статины и высокочувствительные сердечные тропонины: кардиотоксичность или перекрестная реактивность?

АМ Чаулин, ДВ Дупляков - Рациональная фармакотерапия в …, 2023 - cyberleninka.ru
На сегодняшний день гиполипидемические препараты группы статинов являются
одними из самых востребованных терапевтических агентов, применяемых для …