Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance
Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …
most common causes of death worldwide. Since each tumor is unique, there is a need to …
Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation
K Wang, X Wang, Q Pan, B Zhao - Molecular cancer, 2023 - Springer
Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a
potential curative approach for PC, but most patients are unsuitable for operations when at …
potential curative approach for PC, but most patients are unsuitable for operations when at …
Graphene sensor arrays for rapid and accurate detection of pancreatic cancer exosomes in patients' blood plasma samples
T Yin, L Xu, B Gil, N Merali, MS Sokolikova… - ACS …, 2023 - ACS Publications
Biosensors based on graphene field effect transistors (GFETs) have the potential to enable
the development of point-of-care diagnostic tools for early stage disease detection …
the development of point-of-care diagnostic tools for early stage disease detection …
Integrated SERS-vertical flow biosensor enabling multiplexed quantitative profiling of serological exosomal proteins in patients for accurate breast cancer subtyping
Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …
A Single‐Molecule Bioelectronic Portable Array for Early Diagnosis of Pancreatic Cancer Precursors
A cohort of 47 patients is screened for pancreatic cancer precursors with a portable 96‐well
bioelectronic sensing‐array for single‐molecule assay in cysts fluid and blood plasma …
bioelectronic sensing‐array for single‐molecule assay in cysts fluid and blood plasma …
Pancreatic cancer: changing epidemiology and new approaches to risk assessment, early detection, and prevention
EM Stoffel, RE Brand, M Goggins - Gastroenterology, 2023 - Elsevier
Pancreatic cancer usually results in poor survival with limited options for treatment, as most
affected individuals present with advanced disease. Early detection of preinvasive …
affected individuals present with advanced disease. Early detection of preinvasive …
[HTML][HTML] Methylation biomarkers for early cancer detection and diagnosis: Current and future perspectives
J Ibrahim, M Peeters, G Van Camp… - European Journal of …, 2023 - Elsevier
The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …
insights into the field. Moreover, novel technological breakthroughs such as long read …
Artificial intelligence (AI) and machine learning (ML) in precision oncology: a review on enhancing discoverability through multiomics integration
Multiomics data including imaging radiomics and various types of molecular biomarkers
have been increasingly investigated for better diagnosis and therapy in the era of precision …
have been increasingly investigated for better diagnosis and therapy in the era of precision …
Absolute quantification of serum exosomes in patients with an sers-lateral flow strip biosensor for noninvasive clinical cancer diagnosis
Exosomes (exos) widely existing in body fluids show great potential for noninvasive cancer
diagnosis. Quantitative analysis of exos is traditionally performed by targeting specific …
diagnosis. Quantitative analysis of exos is traditionally performed by targeting specific …
Diagnostic accuracy and added value of blood-based protein biomarkers for pancreatic cancer: a meta-analysis of aggregate and individual participant data
Background Novel blood-based protein biomarkers may be of value for efficient, accurate,
and non-invasive diagnosis of pancreatic cancer. This study assesses the diagnostic …
and non-invasive diagnosis of pancreatic cancer. This study assesses the diagnostic …