Background Device-detected atrial high-rate episodes (AHREs) are atrial arrhythmias
detected by implanted cardiac devices. AHREs resemble atrial fibrillation but are rare and …

In contrast to current guidelines and earlier trials, recent studies demonstrated superiority of
rhythm-over rate-control and challenged the strategy of" rate versus rhythm" therapy in …

Atrial fibrillation is the most common atrial arrhythmia and accounts for a significant burden
of cardiovascular disease globally. With advances in implanted and wearable cardiac …

Heart failure (HF) is a major disease in our society that often presents with multiple
comorbidities with mutual interaction and aggravation. The comorbidity of HF and stroke is a …

Stroke is a major complication of atrial fibrillation (AF). About 25% of ischaemic stroke are
cardio-embolic in origin; AF is the most common cause of those. 1 Nonvalvular AF carries a …

BACKGROUND: Sustained forms of atrial fibrillation (AF) are associated with lower
treatment success rates and poorer prognosis compared with paroxysmal AF. Yet, little is …

Uninterrupted anticoagulation for atrial fibrillation (AF), regardless of AF burden, is deeply
rooted in practice since the early anticoagulation trials. However, uninterrupted …

Carotid atherosclerotic disease continues to be an important cause of stroke, often disabling
or fatal. Such strokes could be largely prevented through optimal medical therapy and …

Background Non-valvular atrial fibrillation is associated with the incidence of
thromboembolism. Current guidelines recommend preferential use of novel oral …

In 2014, Hart et al. introduced the concept of “embolic stroke of undetermined
source”(ESUS) to the clinical-research stroke community. The hypothesis underlying the …