Simple Summary Leptomeningeal disease in melanoma (LMM) patients is characterized by
aggressiveness and dismal outcomes. Clinical studies and case reports demonstrate the …

Melanoma is the most aggressive type of skin cancer, with a greater risk of metastasis and a
higher prevalence and mortality rate. This cancer type has been demonstrated to develop …

Abstract Background Immune checkpoint inhibitors (ICIs) have substantially improved
overall survival in patients with advanced melanoma; however, the lack of biomarkers to …

Simple Summary Most melanoma patients have non-overlapping “driver” mutations in either
BRAF, NRAS, or NF1 genes based on Next-Gen sequencing. Other overlapping genetic …

Melanoma, a lethal malignancy that arises from melanocytes, exhibits a multiplicity of clinico‐
pathologically distinct subtypes in sun‐exposed and non‐sun‐exposed areas. Melanocytes …

Skin cancer is one of the most prevalent cancers in the Caucasian population. In the United
States, it is estimated that at least one in five people will develop skin cancer in their lifetime …

Melanoma is the most dangerous form of skin cancer that develops from the malignant
transformation of the melanocytes located in the basal layer of the epidermis (cutaneous …

Loss of protein expression of the tumor suppressor PTEN is associated with increased
cancer aggressiveness, decreased tumor immune infiltration, and resistance to immune and …

Objective: The aim of the present study was to analyze mutations of the mast/stem cell
growth factor receptor Kit (KIT) gene in patients with melanoma from Eastern Siberia regions …

Simple Summary Cutaneous melanoma (CM) accounts for the majority of skin cancer-
related deaths and, during recent decades, its incidence has increased worldwide. Although …