Recent advances in top‐down proteome sample processing ahead of MS analysis

JL Nickerson, V Baghalabadi… - Mass Spectrometry …, 2023 - Wiley Online Library
Top‐down proteomics is emerging as a preferred approach to investigate biological
systems, with objectives ranging from the detailed assessment of a single protein …

Characterization of unbranched ubiquitin tetramers by combining ultraviolet photodissociation with proton transfer charge reduction reactions

A Bashyal, SD Dunham, JS Brodbelt - Analytical Chemistry, 2023 - ACS Publications
Polyubiquitination is an important post-translational modification (PTM) that regulates
various biological functions. The linkage sites and topologies of polyubiquitination chains …