Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement
S Petersenn, M Fleseriu, FF Casanueva… - Nature Reviews …, 2023 - nature.com
Abstract This Consensus Statement from an international, multidisciplinary workshop
sponsored by the Pituitary Society offers evidence-based graded consensus …
sponsored by the Pituitary Society offers evidence-based graded consensus …
Biological and therapeutic implications of the tumor microenvironment in pituitary adenomas
Pituitary adenomas (PAs) are neoplasms derived from the endocrine cells of the anterior
pituitary gland. Most frequently, they are benign tumors, but may sometimes display an …
pituitary gland. Most frequently, they are benign tumors, but may sometimes display an …
Aggressive pituitary tumors and pituitary carcinomas: from pathology to treatment
P Burman, O Casar-Borota… - The Journal of …, 2023 - academic.oup.com
Aggressive pituitary tumors (APTs) and pituitary carcinomas (PCs) are heterogeneous with
regard to clinical presentation, proliferative markers, clinical course, and response to …
regard to clinical presentation, proliferative markers, clinical course, and response to …
Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification
In the 2022 fifth edition of the WHO Classification of Endocrine Tumours and of Central
Nervous System Tumours, pituitary adenomas are reclassified as neuroendocrine tumours …
Nervous System Tumours, pituitary adenomas are reclassified as neuroendocrine tumours …
Therapeutic targeting of the pituitary tumor microenvironment
MD Ilie, D De Alcubierre, AL Carretti… - Pharmacology & …, 2023 - Elsevier
The tumor microenvironment (TME), the complex environment in which tumors develop, has
been increasingly targeted for cancer treatment in recent years. Aggressive pituitary tumors …
been increasingly targeted for cancer treatment in recent years. Aggressive pituitary tumors …
Prevalence and clinical correlations of SF3B1 variants in lactotroph tumours
J Simon, LG Perez-Rivas, Y Zhao… - European journal of …, 2023 - academic.oup.com
Objective A somatic mutational hotspot in the SF3B1 gene was reported in lactotroph
tumours. The aim of our study was to examine the prevalence of driver SF3B1 variants in a …
tumours. The aim of our study was to examine the prevalence of driver SF3B1 variants in a …
An individualized approach to the management of Cushing disease
M Fleseriu, EV Varlamov, JM Hinojosa-Amaya… - Nature Reviews …, 2023 - nature.com
Cushing disease caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary
corticotroph adenoma leads to hypercortisolaemia with high mortality due to metabolic …
corticotroph adenoma leads to hypercortisolaemia with high mortality due to metabolic …
The immune microenviroment in somatotropinomas: from biology to personalized and target therapy
S Chiloiro, L De Marinis - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Pituitary tumors are rare neoplasms, with a heterogeneous biological and clinical behavior,
due to their clinical course, local invasive growth, resistance to conventional therapies and …
due to their clinical course, local invasive growth, resistance to conventional therapies and …
Position statement on the diagnosis and management of acromegaly: the French National Diagnosis and Treatment Protocol (NDTP)
Acromegaly is a rare disease with prevalence of approximately 60 cases per million, slight
female predominance and peak onset in adults in the fourth decade. Clinical diagnosis is …
female predominance and peak onset in adults in the fourth decade. Clinical diagnosis is …
Radiotherapy in aggressive or dopamine agonists resistant prolactinomas; is it still worthwhile?
DA Niculescu, ML Gheorghiu… - European Journal of …, 2023 - academic.oup.com
Radiotherapy, conventional or radiosurgery, has been used to control prolactin secretion
and tumour growth in prolactinomas both as part of multimodal therapy or rarely as primary …
and tumour growth in prolactinomas both as part of multimodal therapy or rarely as primary …