Simple Summary Biliary tract cancers (BTCs), comprising cancers of the bile ducts
(cholangiocarcinoma) as well as gallbladder cancers, continue to be challenging to treat …

Background Cancer immunity is based on the interaction of a multitude of cells in the spatial
context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated …

Background Lung cancer remains the major cause of cancer‐related deaths worldwide.
Early stages of lung cancer are characterized by long asymptomatic periods that are …

Fibroblast activation protein (FAP) is a cell surface serine protease that is highly expressed
on reactive stromal fibroblasts, such as cancer-associated fibroblasts (CAFs), and generally …

Tumor-associated stroma in breast cancer (BC) is complex and exhibits a high degree of
heterogeneity. To date, no standardized assessment method has been established. Artificial …

The study aimed to investigate correlations between HHLA2 levels and parameters,
including microsatellite instability (MSI) status, CD8+ cells, and histopathological features …

Pancreatic ductal adenocarcinoma (PDAC) has a dense stroma, responsible for up to 80%
of its volume. The amount of stroma can be associated with prognosis, although there are …

Background The tumor stroma is composed of a complex network of non-cancerous cells
and extracellular matrix elements that collectively are crucial for cancer progression and …