The function and regulation of heat shock transcription factor in Cryptococcus

C Suo, Y Gao, C Ding, T Sun - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Cryptococcus species are opportunistic human fungal pathogens. Survival in a hostile
environment, such as the elevated body temperatures of transmitting animals and humans …

Off-label treatments as potential accelerators in the search for the ideal antifungal treatment of cryptococcosis

V Alves, GRS Araújo, S Frases - Future Microbiology, 2023 - Taylor & Francis
Cryptococcosis is an opportunistic mycosis that mainly affects immunosuppressed patients.
The treatment is a combination of three antifungal agents: amphotericin B, 5-flucytosine and …

Antifungal activity of selective serotonin reuptake inhibitors against Cryptococcus spp. and their possible mechanism of action

CR da Silva, LGAV Sá, TL Ferreira, AC Leitão… - Journal of Medical …, 2023 - Elsevier
Fungal infections caused by Cryptococcus spp. pose a threat to health, especially in
immunocompromised individuals. The available arsenal of drugs against cryptococcosis is …

Effect of rapamycin on Cryptococcus neoformans: cellular organization, biophysics and virulence factors

IB de Andrade, V Alves, L Pereira, B Miranda… - Future …, 2023 - Taylor & Francis
Background: Cryptococcus neoformans is an opportunistic fungal pathogen that causes
infections mainly in immunosuppressed individuals, such as transplant recipients. Aims: This …

Assessing the In Vitro Potential of Glatiramer Acetate (Copaxone®) as a Chemotherapeutic Candidate for the Treatment of Cryptococcus neoformans Infection

V Alves, PH Martins, B Miranda, IB de Andrade… - Journal of Fungi, 2023 - mdpi.com
Cryptococcosis is a systemic mycosis affecting immunosuppressed individuals, caused by
various Cryptococcus species. The current treatment utilizes a combination of antifungal …

Wood Degradation by Fomitiporia mediterranea M. Fischer: Exploring Fungal Adaptation Using Metabolomic Networking

M Schilling, M Levasseur, M Barbier, L Oliveira-Correia… - Journal of Fungi, 2023 - mdpi.com
Fomitiporia mediterranea M. Fischer (Fmed) is a white-rot wood-decaying fungus associated
with one of the most important and challenging diseases in vineyards: Esca. To relieve …

Multi-target activity of copper complexes: Antibacterial, DNA binding, and molecular docking with SARS-CoV-2 receptor

P Arthi, M Dharmasivam, B Kaya… - Chemico-Biological …, 2023 - Elsevier
A series of pendant-armed mixed-ligand copper (II) complexes of the type [CuL 1-3
(diimine)](1–6) have been synthesized by the reaction of pendant-armed ligands N, N-bis (2 …

Mitochondria in Cryptococcus: an update of mitochondrial transcriptional regulation in Cryptococcus

Y Meng, C Ding - Current genetics, 2023 - Springer
Encapsulated Cryptococcus species are responsible for approximately 15% of AIDS-related
mortality. Numerous intriguing investigations have demonstrated that mitochondria play a …

A Landscape of the Genomic Structure of Cryptococcus neoformans in Colombian Isolates

LH Patiño, M Muñoz, AL Ramírez, N Vélez… - Journal of Fungi, 2023 - mdpi.com
Cryptococcus neoformans species complexes are recognized as environmental fungi
responsible for lethal meningoencephalitis in immunocompromised individuals. Despite the …

Ubiquitin Degradation of the AICAR Transformylase/IMP Cyclohydrolase Ade16 Regulates the Sexual Reproduction of Cryptococcus neoformans

L Han, Y Wu, S Xiong, T Liu - Journal of Fungi, 2023 - mdpi.com
F-box protein is a key protein of the SCF E3 ubiquitin ligase complex, responsible for
substrate recognition and degradation through specific interactions. Previous studies have …