Retinal diseases are a rising concern as major causes of blindness in an aging society;
therapeutic options are limited, and the precise pathogenesis of these diseases remains …

Organoid models have been used to address important questions in developmental and
cancer biology, tissue repair, advanced modelling of disease and therapies, among other …

Over the past decade, the utilization of advanced fluorescence microscopy technologies has
presented numerous opportunities to study or re-investigate autofluorescent molecules and …

Pro-inflammatory cytokines contribute to β-cell failure in both Type-1 and Type-2 Diabetes.
Data collected so far allowed to dissect the genomic, transcriptomic, proteomic and …

Fluorescence lifetime imaging microscopy (FLIM) is a popular modality to create additional
contrast in fluorescence images. By carefully analyzing pixel-based nanosecond lifetime …

Accurately modeling tumor biology and testing novel therapies on patient-derived cells is
critically important to developing therapeutic regimens personalized to a patient's specific …

Rationale: Prediabetes can be reversed through lifestyle intervention, but its main pathologic
hallmark, insulin resistance (IR), cannot be detected as conveniently as blood glucose …

Iodine contrast agents are essential for diagnostic purposes in radiology and have
significant medical benefits. However, they pose a risk of causing allergic reactions or …

Traumatic Brain injury-induced disturbances in mitochondrial fission-and-fusion dynamics
have been linked to the onset and propagation of neuroinflammation and …

Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique used to probe the
local environment of fluorophores. The fit-free phasor approach to FLIM data is increasingly …