Prothrombin complex concentrate (PCC) for treatment of trauma-induced coagulopathy: systematic review and meta-analyses

I Hannadjas, A James, R Davenport, C Lindsay… - Critical Care, 2023 - Springer
Background Trauma-induced coagulopathy (TIC) is common in trauma patients with major
hemorrhage. Prothrombin complex concentrate (PCC) is used as a potential treatment for …

Critical appraisal and concerns regarding a meta-analysis on prothrombin complex concentrate (PCC) for trauma-induced coagulopathy: unveiling methodological …

BC Antônio, MS Denardin, HAF Neves, EMH Padrao - Critical Care, 2023 - Springer
We read with interest the paper “Prothrombin complex concentrate (PCC) for treatment of
trauma-induced coagulopathy: systematic review and meta-analyses”[1]. We appreciate our …

Massive Transfusion Adjuncts for the Traumatically Injured Patient

SL Rakestraw, DT Lammers, RD Hardin, D Cox… - Current Trauma …, 2023 - Springer
Abstract Purpose of Review Early resuscitation with blood products for traumatically injured
patients in hemorrhagic shock represents the current standard of care. Evolving literature …

Alternative blood products in trauma

KM Jan, S Mohapatra, TS Moon - Current Opinion in …, 2023 - journals.lww.com
Stabilization of hemorrhage and resuscitation is priority in trauma-induced coagulopathy
treatment. Alternative products such as tranexamic acid, recombinant factors, prothrombic …

O papel do concentrado de complexo protrombrínico no manejo da coagulopatia induzida por trauma: uma revisão integrativa

MLV dos Santos, HBM da Silva, ECR Moura… - Research, Society and …, 2023 - rsdjournal.org
Introduction: Trauma is a disease that kills almost 6 million people every year. The bleeding
resulting from trauma triggers a complex coagulopathy, which requires immediate treatment …

Coagulopathy in the Trauma Patient

B Zangbar, PM Rhee - Acute Care Surgery and Trauma - taylorfrancis.com
Hemorrhagic shock can be compounded by trauma-induced coagulopathy (TIC), which is a
hypocoagulable state that can develop immediately after injury and deteriorates with …