Cannabinoids in neuroinflammatory disorders: Focusing on multiple sclerosis, Parkinsons, and Alzheimers diseases

B Abd‐Nikfarjam, A Dolati‐Somarin… - …, 2023 - Wiley Online Library
The medicinal properties of cannabis and cannabinoid‐derivative are entirely investigated
and known. In addition, the identification of psychotropic plant cannabinoids has led to more …

Potential of dietary hemp and cannabinoids to modulate immune response to enhance health and performance in animals: opportunities and challenges

F Hassan, C Liu, M Mehboob, RM Bilal… - Frontiers in …, 2023 - frontiersin.org
Cannabinoids are a group of bioactive compounds abundantly present in Cannabis sativa
plant. The active components of cannabis with therapeutic potential are known as …

Differential regulation of Cav3.2 and Cav2.2 calcium channels by CB1 receptors and cannabidiol

EK Harding, IA Souza, MA Gandini… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Cannabinoids are a promising therapeutic avenue for chronic
pain. However, clinical trials often fail to report analgesic efficacy of cannabinoids. Inhibition …

[HTML][HTML] Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics

RF Malheiro, H Carmo, F Carvalho, JP Silva - Pharmacological Research, 2023 - Elsevier
Mitochondria play a critical role in the regulation of several biological processes (eg,
programmed cell death, inflammation, neurotransmission, cell differentiation). In recent …

Synaptic plasticity abnormalities in fetal alcohol spectrum disorders

BS Basavarajappa, S Subbanna - Cells, 2023 - mdpi.com
The brain's ability to strengthen or weaken synaptic connections is often termed synaptic
plasticity. It has been shown to function in brain remodeling following different types of brain …

Endocannabinoid regulation of hippocampus-dependent memory

A Figueiredo, JF Cheer - Experimental Neurology, 2023 - Elsevier
Over the past few decades, tremendous work has been dedicated to understanding how
cannabinoids, both endogenous and exogenous, impact the process of learning and …

Neuroinflammation in the Central Nervous System: Exploring the Evolving Influence of Endocannabinoid System

SS Rathod, YO Agrawal, KT Nakhate, MFN Meeran… - Biomedicines, 2023 - mdpi.com
Neuroinflammation is a complex biological process that typically originates as a protective
response in the brain. This inflammatory process is triggered by the release of pro …

Cannabinoid receptors in GtoPdb v. 2023.1

M Abood, SPH Alexander, F Barth… - IUPHAR/BPS Guide …, 2023 - journals.ed.ac.uk
Cannabinoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on
Cannabinoid Receptors [119]) are activated by endogenous ligands that include N …

The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer's Disease

R Ferrisi, F Gado, C Ricardi, B Polini, C Manera… - Journal of Clinical …, 2023 - mdpi.com
Alzheimer's disease (AD) is characterized by massive neuronal death, brain atrophy, and
loss of neurons and synapses, which all lead to a progressive cognitive decline …

Activation of the Cannabinoid Receptors Suppresses Hyperexcitation of Rat Hippocampal Neuronal Networks In Vitro

SA Maiorov, BK Kairat, SG Gaidin… - … ), Supplement Series A …, 2023 - Springer
Cannabinoid receptors (CBRs) play a key role in various physiological processes, including
neurogenesis, synaptic plasticity, immune modulation, cell apoptosis, metabolism …