Targeted therapy for head and neck cancer: signaling pathways and clinical studies

Q Li, Y Tie, A Alu, X Ma, H Shi - Signal transduction and targeted …, 2023 - nature.com
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …

Recent findings on the impact of ErbB receptors status on prognosis and therapy of head and neck squamous cell carcinoma

C Palumbo, M Benvenuto, C Focaccetti… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer type,
has often an aggressive course and is poorly responsive to current therapeutic approaches …

Current state and future directions of EGFR-directed therapy in head and neck cancer

P Tathineni, N Joshi, MJ Jelinek - Current Treatment Options in Oncology, 2023 - Springer
Opinion Statement Epidermal growth factor receptor (EGFR) is commonly overexpressed in
many head and neck squamous cell carcinomas (HNSCC). With the success of EGFR …

Monoclonal antibodies for the treatment of squamous cell carcinoma: A literature review

A Tamimi, A Tamimi, F Sorkheh, SM Asl… - Cancer …, 2023 - Wiley Online Library
Background Squamous cell carcinoma (SCC) is a relatively common and heterogenous
malignancy of different organs, such as the skin, esophagus, and lungs. Although most …

Immune checkpoint inhibitors in the treatment of oesophageal squamous cell carcinoma: where are we and where are we going?

N Chen, X Xu, Y Fan - Therapeutic Advances in Medical …, 2023 - journals.sagepub.com
Oesophageal squamous cell carcinoma (ESCC) is a kind of malignant tumour with high
invasiveness and a poor prognosis. Immunotherapy, especially immune checkpoint …

Regional outcome disparities in German head and neck cancer patients: Shorter survival in Eastern Germany

JM Vahl, G Nagel, T Abou Kors, M Brand… - Cancer …, 2023 - Wiley Online Library
Introduction Demographics are important prognostic factors in malignant diseases. A
nationwide analysis concerning the prognostic impact of demographics in head and neck …

Combination immunochemotherapy for recurrent or metastatic head and neck squamous cell carcinoma: a systematic review and meta-analysis

Q Xu, S Huang, K Yang - BMJ open, 2023 - bmjopen.bmj.com
Objective To evaluate the efficacy and safety of combination immunochemotherapy
regimens for the treatment of recurrent or metastatic head and neck squamous cell …

Recurrent/metastatic head and neck squamous cell carcinoma in older patients: are new agents bringing new hope?

M Cossu Rocca, L Lorini, P Szturz, P Bossi… - Drugs & Aging, 2023 - Springer
Head and neck cancer is a broad family of diseases, most of which are of squamous cell
origin, affecting the epithelial mucosa lining the upper aerodigestive tract. They often recur …

Addition of epidermal growth factor receptor inhibitors to standard chemotherapy increases survival of advanced head and neck squamous cell carcinoma patients: A …

F Kiss, K Pohóczky, A Görbe, F Dembrovszky… - Oral …, 2023 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is among the common tumors
associated with high mortality. The aim of our meta‐analysis was to determine how …

Therapeutic Cancer Vaccines for the Management of Recurrent and Metastatic Head and Neck Cancer: A Review

A Ritter, N Koirala, A Wieland… - … –Head & Neck …, 2023 - jamanetwork.com
Importance Squamous cell carcinoma of the head and neck (HNSCC) is prevalent globally
and in the US. Management, particularly after disease recurrence, can be challenging, and …