The interplay of autophagy and oxidative stress in the kidney: what do we know?
H Guo, W Bechtel-Walz - Nephron, 2023 - karger.com
Background: Autophagy, as an indispensable metabolism, plays pivotal roles in maintaining
intracellular homeostasis. Nutritional stress, amino acid deficiency, oxidative stress, and …
intracellular homeostasis. Nutritional stress, amino acid deficiency, oxidative stress, and …
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis
MJ Livingston, S Shu, Y Fan, Z Li, Q Jiao, XM Yin… - Autophagy, 2023 - Taylor & Francis
Following acute kidney injury (AKI), renal tubular cells may stimulate fibroblasts in a
paracrine fashion leading to interstitial fibrosis, but the paracrine factors and their regulation …
paracrine fashion leading to interstitial fibrosis, but the paracrine factors and their regulation …
[HTML][HTML] Global research trends and hot spots on autophagy and kidney diseases: a bibliometric analysis from 2000 to 2022
S Ai, Y Li, H Zheng, Z Wang, W Liu, JY Tao… - Frontiers in …, 2023 - frontiersin.org
Background: Autophagy is an essential cellular process involving the self-degradation and
recycling of organelles, proteins, and cellular debris. Recent research has shown that …
recycling of organelles, proteins, and cellular debris. Recent research has shown that …
[HTML][HTML] Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways
D Liao, D Shangguan, Y Wu, Y Chen, N Liu, J Tang… - …, 2023 - Springer
Background Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies.
Oxidative stress has been validated as a critical event involved in DOX-induced …
Oxidative stress has been validated as a critical event involved in DOX-induced …
[HTML][HTML] Pioglitazone Protects Tubular Epithelial Cells during Kidney Fibrosis by Attenuating miRNA Dysregulation and Autophagy Dysfunction Induced by TGF-β
A Manzéger, G Garmaa, MM Mózes… - International Journal of …, 2023 - mdpi.com
Excessive renal TGF-β production and pro-fibrotic miRNAs are important drivers of kidney
fibrosis that lack any efficient treatment. Dysfunctional autophagy might play an important …
fibrosis that lack any efficient treatment. Dysfunctional autophagy might play an important …
Inhibition of excessive autophagy alleviates renal injury and inflammation in a rat model of immunoglobulin A nephropathy
M Chang, X Shi, S Ma, M Zhao, J Fan, Z Pan… - European Journal of …, 2023 - Elsevier
The pathogenesis of immunoglobulin A nephropathy (IgAN) is closely related to immunity
and inflammation. The clinical process of IgAN varies greatly, making the assessment of …
and inflammation. The clinical process of IgAN varies greatly, making the assessment of …
[HTML][HTML] How to Best Protect Kidneys for Transplantation—Mechanistic Target
S Akalay, SA Hosgood - Journal of Clinical Medicine, 2023 - mdpi.com
The increasing number of patients on the kidney transplant waiting list underlines the need
to expand the donor pool and improve kidney graft utilization. By protecting kidney grafts …
to expand the donor pool and improve kidney graft utilization. By protecting kidney grafts …
MicroRNAs in septic acute kidney injury
B Wang, J Xu, P Fu, L Ma - Burns & trauma, 2023 - academic.oup.com
Sepsis is a potentially fatal complication of burns and trauma that can cause acute kidney
injury (AKI) with substantial morbidity and mortality, but this disease is poorly understood …
injury (AKI) with substantial morbidity and mortality, but this disease is poorly understood …
[HTML][HTML] Effects of Multiwall Carbon Nanotubes on Premature Kidney Aging: Biochemical and Histological Analysis
Carbon nanotubes (CNTs) have gained much attention due to their superb properties, which
make them promising options for the reinforcing composite materials with desirable …
make them promising options for the reinforcing composite materials with desirable …
Mitigating the nephrotoxic impact of hexavalent chromium in Ctenopharyngodon idellus (grass carp) with Boerhavia diffusa (punarnava) leaf extract
K Handa, R Jindal - Environmental Science and Pollution Research, 2023 - Springer
In Ctenopharyngodon idellus, the ameliorative influence of rutin-containing leaf extract of B
oerhavia diffusa was assessed against chronic exposure to hexavalent chromium. For this …
oerhavia diffusa was assessed against chronic exposure to hexavalent chromium. For this …