Although cardiac action potential (AP) generation and propagation have traditionally been
attributed exclusively to cardiomyocytes (CM), other cell types in the heart are also capable …

Potassium channels are widespread over all kingdoms and play an important role in the
maintenance of cellular ionic homeostasis. Kv1. 3 is a voltage-gated potassium channel of …

Background: Resolution of inflammation is orchestrated by specialized proresolving lipid
mediators (SPMs), and this would be impaired in some cardiovascular diseases. Among …

Experimental evidence indicates that the control of the inflammatory response after
myocardial infarction is a key strategy to reduce cardiac injury. Cellular damage after blood …

Potassium channels are often highly expressed in cancer cells with respect to healthy ones,
as they provide proliferative advantages through modulating membrane potential, calcium …

Ethnopharmacological relevance Inflammation plays pivotal role in the development of
chronic diseases. Reducing chronic inflammation is an important strategy for preventing and …

Immune cells have an important role in the tumor-microenvironment. Macrophages may tune
the immune response toward inflammatory or tolerance pathways. Tumor-associated …

Macrophages are the predominant component of innate immunity, which is an important
protective barrier of our body. Macrophages are present in all organs and tissues of the …

The 6TM family of K channels comprises the voltage-gated KV subfamilies, the EAG
subfamily (which includes hERG channels), the Ca 2+-activated Slo subfamily (actually with …

Voltage‐dependent potassium channel Kv1. 3 plays a key role on T‐cell activation;
however, lack of reliable antibodies has prevented its accurate detection under endogenous …