Risk factors for eating disorders: findings from a rapid review

S Barakat, SA McLean, E Bryant, A Le, P Marks… - Journal of eating …, 2023 - Springer
Background Risk factors represent a range of complex variables associated with the onset,
development, and course of eating disorders. Understanding these risk factors is vital for the …

Transcriptional signatures of heroin intake and relapse throughout the brain reward circuitry in male mice

CJ Browne, R Futamura, A Minier-Toribio, EM Hicks… - Science …, 2023 - science.org
Opioid use disorder (OUD) looms as one of the most severe medical crises facing society.
More effective therapeutics will require a deeper understanding of molecular changes …

Epidemiologic and genetic associations of endometriosis with depression, anxiety, and eating disorders

D Koller, GA Pathak, FR Wendt, DS Tylee… - JAMA Network …, 2023 - jamanetwork.com
Importance Endometriosis is a common chronic gynecologic pathology with a large negative
impact on women's health. Beyond severe physical symptoms, endometriosis is also …

Integrative analyses highlight functional regulatory variants associated with neuropsychiatric diseases

MG Guo, DL Reynolds, CE Ang, Y Liu, Y Zhao… - Nature Genetics, 2023 - nature.com
Noncoding variants of presumed regulatory function contribute to the heritability of
neuropsychiatric disease. A total of 2,221 noncoding variants connected to risk for ten …

Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia …

L Bang, S Bahrami, G Hindley, OB Smeland… - Translational …, 2023 - nature.com
Anorexia nervosa (AN) is a heritable eating disorder (50–60%) with an array of commonly
comorbid psychiatric disorders and related traits. Although significant genetic correlations …

Anorexia Nervosa in Juvenile Systemic Lupus Erythematosus (SLE): A Causality Dilemma

MG Grammatikopoulou, V Syrmou, ML Lioliopoulou… - Children, 2023 - mdpi.com
Juvenile-onset systemic lupus erythematosus (jSLE) is an autoimmune disorder with
multifaceted clinical findings in different organ systems. Neuropsychiatric manifestations …

Gene-environment correlations and genetic confounding underlying the association between media use and mental health

Z Ayorech, JR Baldwin, JB Pingault, K Rimfeld… - Scientific Reports, 2023 - nature.com
The increase in online media use and mental health problems have prompted investigations
into their association, although most literature is focussed on deleterious effects. We …

Mapping anorexia nervosa genes to clinical phenotypes

JS Johnson, AC Cote, A Dobbyn, LG Sloofman… - Psychological …, 2023 - cambridge.org
Background Anorexia nervosa (AN) is a psychiatric disorder with complex etiology, with a
significant portion of disease risk imparted by genetics. Traditional genome-wide association …

Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk

SK Powell, C O'Shea, K Townsley, I Prytkova… - Molecular …, 2023 - nature.com
Dopaminergic neurons are critical to movement, mood, addiction, and stress. Current
techniques for generating dopaminergic neurons from human induced pluripotent stem cells …

Elevated lipid class concentrations in females with anorexia nervosa before and after intensive weight restoration treatment—A lipidomics study

AA Hussain, M Bilgin, J Carlsson… - … Journal of Eating …, 2023 - Wiley Online Library
Objective To study the plasma lipidome of patients with anorexia nervosa (AN) before and
after weight restoration treatment and report associations with AN subtypes and oral …