Applied strategies of neuroplasticity

BP Johnson, LG Cohen - Handbook of clinical neurology, 2023 - Elsevier
Various levels of somatotopic organization are present throughout the human nervous
system. However, this organization can change when needed based on environmental …

Selective TLR4 antagonism prevents and reverses morphine-induced persistent postoperative cognitive dysfunction, dysregulation of synaptic elements, and impaired …

SM Muscat, NP Deems, MJ Butler… - Journal of …, 2023 - Soc Neuroscience
Perioperative neurocognitive disorders (PNDs) are characterized by confusion, difficulty with
executive function, and episodic memory impairment in the hours to months following a …

[HTML][HTML] Short-term high-fat diet consumption impairs synaptic plasticity in the aged hippocampus via IL-1 signaling

BMG Olmo, MN Bettes, JW DeMarsh, F Zhao… - NPJ science of …, 2023 - ncbi.nlm.nih.gov
More Americans are consuming diets higher in saturated fats and refined sugars than ever
before. These trends could have serious consequences for the older population because …

Voluntary running improves behavioral and structural abnormalities in a mouse model of CDKL5 deficiency disorder

N Mottolese, B Uguagliati, M Tassinari, CB Cerchier… - Biomolecules, 2023 - mdpi.com
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a rare
neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene. CDD is …

Exercise‐induced modulation of neuroinflammation in ageing

Z Barad, J Augusto, ÁM Kelly - The Journal of Physiology, 2023 - Wiley Online Library
Optimal performance of the central nervous system (CNS) depends on dynamic,
multidirectional communication between different cell types both within and without the CNS …

A novel transgenic mouse model expressing primate-specific nuclear choline acetyltransferase: insights into potential cholinergic vulnerability

HE AlQot, RJ Rylett - Scientific Reports, 2023 - nature.com
The acetylcholine (ACh) synthesizing enzyme choline acetyltransferase (ChAT) is an
important cholinergic neuronal marker whose levels and/or activity are reduced in …

Short-term high-fat diet consumption impairs synaptic plasticity in the aged hippocampus via IL-1 signaling

BM González Olmo, MN Bettes, JW DeMarsh… - npj Science of …, 2023 - nature.com
More Americans are consuming diets higher in saturated fats and refined sugars than ever
before. These trends could have serious consequences for the older population because …

Bioinformatics Analysis and Experimental Verification of Exercise for Aging Mice in Different Brain Regions Based on Transcriptome Sequencing

Y Jin, C Wei, X Huang, D Zhang, L Zhang, X Li - Life, 2023 - mdpi.com
Purpose: Physical exercise mitigates the effects of aging and cognitive decline. However,
the precise neurobiological mechanisms underlying this phenomenon remain unclear. The …

Post-Operative Neurocognitive Disorder: Potentiating Factors and the Role of Toll-Like Receptor 4

SM Muscat - 2023 - search.proquest.com
The work described herein aims to fill a gap in knowledge regarding specific mechanisms
that underlie the development of persistent cognitive impairments following surgery …

The Association Between Aerobic Fitness and Network Connectivity in the Default Mode Network in Healthy Adolescents and Young Adults

KN Leclaire - 2023 - search.proquest.com
The beneficial effects of aerobic fitness on psychiatric and cognitive function in older adults
have been well demonstrated in existing literature. However, less remains known about the …