Circular ribonucleic acids (circRNAs) are widely expressed in cells and tissues and play vital
roles in cellular physiological processes. Their expressions are associated with …

Satellite DNA is characterized by long, tandemly repeated sequences mainly found in
centromeres and pericentromeric chromosomal regions. The recent advent of telomere‐to …

3-3 proteins are highly conserved regulatory proteins that interact with hundreds of
structurally diverse clients and act as central hubs of signaling networks. However, how 14-3 …

The glioblastoma (GBM) stem cell–like cells (GSCs) are critical for tumorigenesis/therapeutic
resistance of GBM. Mounting evidence supports tumor-promoting function of long noncoding …

Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been
implicated in various regulatory mechanisms across the animal kingdom and particularly in …

Amyotrophic lateral sclerosis (ALS) is characterized by nucleocytoplasmic mislocalization of
the RNA-binding protein (RBP) TDP-43. However, emerging evidence suggests more …

Summary 3′ untranslated region (3′ UTR) somatic mutations represent a largely
unexplored avenue of alternative oncogenic gene dysregulation. To determine the …

U6 snRNA is a catalytic RNA responsible for pre-mRNA splicing reactions and undergoes
various post-transcriptional modifications during its maturation process. The 3' …

Targeting the PI3K–AKT–mTOR pathway is a promising therapeutic strategy for breast
cancer treatment. However, low response rates and development of resistance to PI3K–AKT …

Machine learning methods, particularly neural networks trained on large datasets, are
transforming how scientists approach scientific discovery and experimental design …