Reactive nitrogen species as therapeutic targets for autophagy/mitophagy modulation to relieve neurodegeneration in multiple sclerosis: Potential application for drug …
Multiple sclerosis (MS) is a neuroinflammatory disease with limited therapeutic effects,
eventually developing into handicap. Seeking novel therapeutic strategies for MS is timely …
eventually developing into handicap. Seeking novel therapeutic strategies for MS is timely …
Regulated arginine metabolism in immunopathogenesis of a wide range of diseases: is there a way to pass between scylla and charybdis?
EA Starikova, AA Rubinstein, JT Mammedova… - Current Issues in …, 2023 - mdpi.com
More than a century has passed since arginine was discovered, but the metabolism of the
amino acid never ceases to amaze researchers. Being a conditionally essential amino acid …
amino acid never ceases to amaze researchers. Being a conditionally essential amino acid …
Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS
Ferroptosis is a form of lipid peroxidation-mediated cell death and damage triggered by
excess iron and insufficiency in the glutathione antioxidant pathway. Oxidative stress is …
excess iron and insufficiency in the glutathione antioxidant pathway. Oxidative stress is …
Effects of N‐acetylcysteine on oxidative stress biomarkers, depression, and anxiety symptoms in patients with multiple sclerosis
G Khalatbari Mohseni, SA Hosseini… - …, 2023 - Wiley Online Library
Abstract Aim N‐acetylcysteine (NAC), a thiol‐containing antioxidant and glutathione (GSH)
precursor, attenuates oxidative stress, and possibly improves psychiatric disorders. This …
precursor, attenuates oxidative stress, and possibly improves psychiatric disorders. This …
Ferroptosis in neurological disease
Iron accumulation in the CNS occurs in many neurological disorders. It can contribute to
neuropathology as iron is a redox-active metal that can generate free radicals. The reasons …
neuropathology as iron is a redox-active metal that can generate free radicals. The reasons …
Therapeutic plasma exchange in certain immune-mediated neurological disorders: focus on a novel nanomembrane-based technology
DG Tonev, AB Momchilova - Biomedicines, 2023 - mdpi.com
Therapeutic plasma exchange (TPE) is an efficient extracorporeal blood purification
technique to remove circulating autoantibodies and other pathogenic substances. Its …
technique to remove circulating autoantibodies and other pathogenic substances. Its …
[HTML][HTML] Improvement effects of green tea and pumpkin oils on myelin oligodendrocyte glycoprotein-induced Multiple sclerosis in rats
NS Lamloum, HA Soliman, RR Ahmed… - Journal of Functional …, 2023 - Elsevier
Multiple sclerosis (MS) is a demyelinating disorder of the central nervous system (CNS)
associated with significant progressive neurodegeneration. There is a lot of interest in the …
associated with significant progressive neurodegeneration. There is a lot of interest in the …
Metabolomics of Cerebrospinal Fluid Amino and Fatty Acids in Early Stages of Multiple Sclerosis
M Židó, D Kačer, K Valeš, D Zimová… - International Journal of …, 2023 - mdpi.com
Multiple sclerosis (MS) is a demyelinating and neurodegenerative autoimmune disease of
the central nervous system (CNS) damaging myelin and axons. Diagnosis is based on the …
the central nervous system (CNS) damaging myelin and axons. Diagnosis is based on the …
[HTML][HTML] Mitogen-activated protein kinase inhibitor PD98059 improves neuroimmune dysfunction in experimental autoimmune encephalomyelitis in SJL/J mice …
Multiple sclerosis (MS) is a severe autoimmune disease leading to demyelination, followed
by consequent axonal degeneration, causing sensory, motor, cognitive, and visual …
by consequent axonal degeneration, causing sensory, motor, cognitive, and visual …
Nanowired delivery of antibodies to tau and neuronal nitric oxide synthase together with cerebrolysin attenuates traumatic brain injury induced exacerbation of brain …
A Ozkizilcik, A Sharma, L Feng, DF Muresanu… - International Review of …, 2023 - Elsevier
Concussive head injury (CHI) is one of the major risk factors for developing Parkinson's
disease in later life of military personnel affecting lifetime functional and cognitive …
disease in later life of military personnel affecting lifetime functional and cognitive …