Cell fate is shaped by a unique gene expression program, which reflects the concerted
action of multilayered precise regulation. Substantial research attention has been paid to the …

Background CircRNA is recognized for its significant regulatory function across various
cancers. However, its regulatory role in non-small cell lung cancer (NSCLC) is still largely …

Abstract Purpose of Review The underlying molecular mechanisms that direct stem cell
differentiation into fully functional, mature cells remain an area of ongoing investigation. Cell …

Abstract NOT1, NOT10, and NOT11 form a conserved module in the CCR4-NOT complex,
critical for post-transcriptional regulation in eukaryotes, but how this module contributes to …

RNA-binding proteins (RBPs) are key regulators of gene expression, but how RBPs convey
regulatory instructions to the core effectors of RNA processing is unclear. Here we document …

Gynecological cancers pose a threat to women's health. Although early-stage gynecological
cancers show good outcomes after standardized treatment, the prognosis of patients with …

The RNA-protein interplay has been proven to be essential for precise regulation of both
RNA and protein, which has many implications in various biological processes including …

Post-transcriptional regulation includes both RNA and protein modifications, leading to the
modulation of protein expression levels or protein functions. These modifications may …

Abstract Changes in gene expression implement signalling pathways to drive cell fate
transitions 1, 2. However, the mechanisms for rapid and selective transcriptome rewiring in …

Durante la última década, gracias a los avances en las tecnologías de secuenciación
masiva que han permitido un análisis más profundo de los transcriptomas de varios …