[HTML][HTML] Health inequalities in the management of chronic hepatitis B virus infection in patients from sub-Saharan Africa in high-income countries
T Mitchell, JS Nayagam, G Dusheiko, K Agarwal - JHEP Reports, 2023 - Elsevier
Chronic hepatitis B virus disproportionately affects migrant communities in high-income
countries, reflecting increased migration from sub-Saharan Africa. Chronic hepatitis B virus …
countries, reflecting increased migration from sub-Saharan Africa. Chronic hepatitis B virus …
Bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir, emtricitabine, and tenofovir disoproxil fumarate for initial treatment of HIV-1 and hepatitis B …
A Avihingsanon, H Lu, CL Leong, CC Hung… - The Lancet …, 2023 - thelancet.com
Background For most adults with HIV-1 and hepatitis B virus (HBV) coinfection, initial
recommended treatment is a tenofovir-containing antiretroviral regimen, but no randomised …
recommended treatment is a tenofovir-containing antiretroviral regimen, but no randomised …
Treatment endpoints for chronic hepatitis D
O Metin, M Zeybel, C Yurdaydin - Liver International, 2023 - Wiley Online Library
Management of chronic hepatitis D (CHD) has entered a new era. In this new era, the virus
entry inhibitor bulevirtide has received conditional approval as a treatment for compensated …
entry inhibitor bulevirtide has received conditional approval as a treatment for compensated …
[HTML][HTML] Chinese herbal formula ruangan granule enhances the efficacy of entecavir to reverse advanced liver fibrosis/early cirrhosis in patients with chronic HBV …
Y Xing, W Zhong, D Peng, Z Han, H Zeng… - Pharmacological …, 2023 - Elsevier
Background Nucleotide analogs treatment can reverse liver fibrosis in chronic hepatitis B
(CHB). However, it has limited effect on fibrosis resolution in patients with CHB, particularly …
(CHB). However, it has limited effect on fibrosis resolution in patients with CHB, particularly …
[HTML][HTML] Interferon stimulated immune profile changes in a humanized mouse model of HBV infection
Y Wang, L Guo, J Shi, J Li, Y Wen, G Gu, J Cui… - Nature …, 2023 - nature.com
The underlying mechanism of chronic hepatitis B virus (HBV) functional cure by interferon
(IFN), especially in patients with low HBsAg and/or young ages, is still unresolved due to the …
(IFN), especially in patients with low HBsAg and/or young ages, is still unresolved due to the …
Cost‐effectiveness of treating all hepatitis B–positive individuals in the United States
D Razavi‐Shearer, C Estes… - Journal of Viral …, 2023 - Wiley Online Library
Chronic hepatitis B virus (HBV) infection is a leading cause of liver disease and related
mortality globally. However, most of the infected individuals in the United States remain …
mortality globally. However, most of the infected individuals in the United States remain …
[HTML][HTML] Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells
Background & Aims Patterns of liver HBV antigen expression have been described but not
quantified at single-cell resolution. We applied quantitative techniques to liver biopsies from …
quantified at single-cell resolution. We applied quantitative techniques to liver biopsies from …
[HTML][HTML] Tenofovir use is associated with a decreased risk of hepatocellular carcinoma among men with HIV irrespective of coinfection status
MH Lee, PF Wu, TI Chen, C Chan, HH Lin, YH Huang… - JHEP Reports, 2023 - Elsevier
Background & Aims Tenofovir is recommended as part of the first-line antiretroviral therapy
(ART) to treat people living with HIV (PLWH) with HBV coinfection. However, the effects of …
(ART) to treat people living with HIV (PLWH) with HBV coinfection. However, the effects of …
Overview of the development of HBV small molecule inhibitors
H Yang, W Yao, J Yang - European Journal of Medicinal Chemistry, 2023 - Elsevier
Abstract Like tuberculosis and Acquired Immune Deficiency Syndrome (AIDS), hepatitis B is
a globally recognized major public health threat. Although there are many small-molecule …
a globally recognized major public health threat. Although there are many small-molecule …
Clinical trials in hepatitis D virus: Measuring success
BL Da - Hepatology, 2023 - journals.lww.com
Chronic hepatitis D infection results in the most severe form of chronic viral hepatitis but
currently lacks effective treatment options. Therapy with pegylated interferon alpha is …
currently lacks effective treatment options. Therapy with pegylated interferon alpha is …