Integrative metabolomics science in Alzheimer's disease: relevance and future perspectives
Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …
How far are we from reliable metabolomics-based biomarkers? The often-overlooked importance of addressing inter-individual variability factors
Á González-Domínguez… - Biochimica et Biophysica …, 2023 - Elsevier
Metabolomics has proven great potential to unravel the molecular basis of diseases.
However, most attempts aimed at identifying reliable metabolomics-based biomarkers for …
However, most attempts aimed at identifying reliable metabolomics-based biomarkers for …
Rat hair metabolomics analysis reveals perturbations of unsaturated fatty acid biosynthesis, phenylalanine, and arachidonic acid metabolism pathways are associated …
TH Tan, SW Li, CW Chang, YC Chen, YH Liu… - Molecular …, 2023 - Springer
Hair is a noninvasive valuable biospecimen for the long-term assessment of endogenous
metabolic disturbance. Whether the hair is suitable for identifying biomarkers of the …
metabolic disturbance. Whether the hair is suitable for identifying biomarkers of the …
Analysis and Annotation of Phospholipids by Mass Spectrometry-Based Metabolomics
Á González-Domínguez, M Santos-Martín… - … : Methods and Protocols, 2023 - Springer
Phospholipids are essential components of membrane lipid bilayers and serve as
precursors of multiple signaling molecules, so alterations in their homeostasis are …
precursors of multiple signaling molecules, so alterations in their homeostasis are …