Regulation of the Blood–Brain Barrier in Health and Disease

CC Rada, K Yuki, J Ding… - Cold Spring …, 2023 - perspectivesinmedicine.cshlp.org
The neurovascular unit is a dynamic microenvironment with tightly controlled signaling and
transport coordinated by the blood–brain barrier (BBB). A properly functioning BBB allows …

BCL6B contributes to ocular vascular diseases via Notch signal silencing

M Tanaka, S Nakamura, T Sakaue… - … and Vascular Biology, 2023 - Am Heart Assoc
Background: Endothelial cell activation is tightly controlled by the balance between VEGF
(vascular endothelial cell growth factor) and Notch signaling pathway. VEGF destabilizes …

[18F]AlF-NOTA-ADH-1: A new PET molecular radiotracer for imaging of N-cadherin-positive tumors

Z Liu, G Wen, Y Huang, Y Dong, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Background The cell adhesion molecule (CAM) N-cadherin has become an important target
for tumor therapy. The N-cadherin antagonist, ADH-1, exerts significant antitumor activity …

Untersuchungen zur Bedeutung von Spaltprodukten des vaskulär endothelialen (VE-) Cadherin als Auslöser für die Schrankenstörung des Gefäßendothels

JL Knop - 2023 - opus.bibliothek.uni-wuerzburg.de
Ein Schlüsselereignis, welches dem prognosebestimmenden Organversagen bei systemi-
schen Entzündungsprozessen und Sepsis vorangeht, ist die Entwicklung einer mikrovas …