[HTML][HTML] Ventral hippocampal diacylglycerol lipase-alpha deletion decreases avoidance behaviors and alters excitation-inhibition balance

V Kondev, R Bluett, M Najeed, LE Rosas-Vidal… - Neurobiology of …, 2023 - Elsevier
Abstract The endogenous cannabinoid, 2-arachidonoylglycerol (2-AG), plays a key role in
the regulation of anxiety-and stress-related behavioral phenotypes and may represent a …

The estrous cycle influences the effects of fatty acid amide hydrolase and monoacylglycerol lipase inhibition in the anxiety-like behavior in rats

BW Salemme, AM Raymundi, JMB Sohn… - Cannabis and …, 2023 - liebertpub.com
Background: Sex differences in the response to the anxiety-related effects of cannabinoid
drugs have been reported, with females being more sensitive than males. Evidence …

Fatty acid amide hydrolase inhibitor URB597 suppressed conditioned and sensitized fear responses in a rat model of post-traumatic stress disorder

M Dargahi, G Karimi, L Etemad, MS Alavi… - Learning and …, 2023 - Elsevier
Background Post-traumatic stress disorder (PTSD) is a debilitating disorder that results from
exposure to various traumatic events. Endocannabinoids levels change during PTSD …

Underlying mechanisms of long-term potentiation during the inhibition of the cannabinoid CB1 and GABAB receptors in the dentate gyrus of hippocampus

M Nazari, SA Karimi, S Komaki, M Kourosh Arami… - BMC neuroscience, 2023 - Springer
Background The release of various neurotransmitters and thereby the excitability of
neuronal circuits are regulated by the endocannabinoid system in an activity-dependent …