Coronary artery disease (CAD) is highly prevalent in older adults, yet its management
remains challenging. Treatment choices are made complex by the frailty burden of older …

The biological clock system is an intrinsic timekeeping device that integrates internal
physiology and external cues. Maintaining a healthy biological clock system is crucial for life …

Objective: To elucidate the bidirectional correlation of sarcopenia with coronary heart
disease (CHD), as well as to investigate the mediating role of cardiometabolic factors and …

Background Living alone can cause social isolation and is correlated with multiple adverse
health outcomes. Evidence about the association of living alone and social isolation with …

Fibroblast growth factor 21 (FGF21) plays a vital role in normal eukaryotic organism
development and homeostatic metabolism under the influence of internal and external …

Background Malnutrition may be an important geriatric condition in adults with heart failure
with preserved ejection fraction (HFpEF), but studies on its prevalence and associated …

We review a comprehensive risk assessment approach for percutaneous coronary
interventions in older adults and highlight the relevance of geriatric syndromes within that …

Background and objective Cardiovascular disease (CVD) is the leading cause of morbidity
and mortality in the United States. However, current evidence on the association between …

As the population ages, older adults represent an increasing proportion of patients referred
to the cardiac catheterization laboratory. Older adults are the highest-risk group for morbidity …

Background: The renin-angiotensin system (RAS) activation is a proposed mechanism of
muscle wasting (MW ie, reduction in muscle mass). Although we reported that RAS inhibitors …