Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …
Diagnosis and management of autoimmune hepatitis
L Muratori, AW Lohse, M Lenzi - bmj, 2023 - bmj.com
Autoimmune hepatitis is an inflammatory disease of the liver of unknown cause that may
progress to liver cirrhosis and end stage liver failure if diagnosis is overlooked and treatment …
progress to liver cirrhosis and end stage liver failure if diagnosis is overlooked and treatment …
AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …
Lenvatinib combined with transarterial chemoembolization as first-line treatment for advanced hepatocellular carcinoma: a phase III, randomized clinical trial …
Z Peng, W Fan, B Zhu, G Wang, J Sun… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Lenvatinib (LEN) is a first-line therapy for patients with advanced hepatocellular
carcinoma (HCC); however, it has shown modest survival benefits. Therefore, we aimed to …
carcinoma (HCC); however, it has shown modest survival benefits. Therefore, we aimed to …
AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …
A multidisciplinary approach to the diagnosis and management of Wilson disease: Executive summary of the 2022 Practice Guidance on Wilson disease from the …
ML Schilsky, EA Roberts, JM Bronstein, A Dhawan… - Hepatology, 2023 - journals.lww.com
Copper is an essential metal required for many metalloproteins' function. A fraction of dietary
copper (average 2–5 mg/day) is absorbed by enterocytes in the duodenum and proximal …
copper (average 2–5 mg/day) is absorbed by enterocytes in the duodenum and proximal …
Detecting liver cancer using cell-free DNA fragmentomes
ZH Foda, AV Annapragada, K Boyapati, DC Bruhm… - Cancer discovery, 2023 - AACR
Liver cancer is a major cause of cancer mortality worldwide. Screening individuals at high
risk, including those with cirrhosis and viral hepatitis, provides an avenue for improved …
risk, including those with cirrhosis and viral hepatitis, provides an avenue for improved …
Eliminating METTL1‐mediated accumulation of PMN‐MDSCs prevents hepatocellular carcinoma recurrence after radiofrequency ablation
X Zeng, G Liao, S Li, H Liu, X Zhao, S Li, K Lei… - Hepatology, 2023 - journals.lww.com
Conclusions: Our study sheds light on the pivotal role of METTL1 in modulating an
immunosuppressive microenvironment and demonstrated that interrupting METTL1‐TGF‐β2 …
immunosuppressive microenvironment and demonstrated that interrupting METTL1‐TGF‐β2 …
[HTML][HTML] Chronic liver disease
Objectives: Identify the etiology of chronic liver disease. Outline the appropriate evaluation of
chronic liver disease. Review the treatment options available for chronic liver disease …
chronic liver disease. Review the treatment options available for chronic liver disease …
[HTML][HTML] Immunotherapy for hepatocellular carcinoma: Current status and future perspectives
DS Mandlik, SK Mandlik… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the world's deadliest and fastest-growing tumors,
with a poor prognosis. HCC develops in the context of chronic liver disease. Curative …
with a poor prognosis. HCC develops in the context of chronic liver disease. Curative …