Clinical usefulness of scoring systems to predict severe acute pancreatitis: A systematic review and meta‐analysis with pre and post‐test probability assessment

G Capurso, R Ponz de Leon Pisani… - United European …, 2023 - Wiley Online Library
Background Scoring systems for severe acute pancreatitis (SAP) prediction should be used
in conjunction with pre‐test probability to establish post‐test probability of SAP, but data of …

[HTML][HTML] Controversies in the management of acute pancreatitis: An update

M Manrai, S Dawra, AK Singh, DK Jha… - World Journal of …, 2023 - ncbi.nlm.nih.gov
This review summarized the current controversies in the management of acute pancreatitis
(AP). The controversies in management range from issues involving fluid resuscitation …

Establishment and validation of a nomogram prediction model for the severe acute pancreatitis

B Li, W Wu, A Liu, L Feng, B Li, Y Mei… - Journal of …, 2023 - Taylor & Francis
Background Severe acute pancreatitis (SAP) can progress to lung and kidney dysfunction,
and blood clotting within 48 hours of its onset, and is associated with a high mortality rate …

The East Asian-specific LPL p.Ala288Thr (c.862G > A) missense variant exerts a mild effect on protein function

Y Hu, G Zhang, Q Yang, N Pu, K Li, B Li… - Lipids in Health and …, 2023 - Springer
Background Lipoprotein lipase (LPL) is the key enzyme responsible for the hydrolysis of
triglycerides. Loss-of-function variants in the LPL gene are associated with …

Clinical characteristics and risk factors of organ failure and death in necrotizing pancreatitis

L Yu, F Xie, L Luo, Y Lei, X Huang, X Yang, Y Zhu… - BMC …, 2023 - Springer
Background Organ failure (OF) and death are considered the most significant adverse
outcomes in necrotizing pancreatitis (NP). However, there are few NP-related studies …

Identification and characterization of pancreatic infections in severe and critical acute pancreatitis patients using 16S rRNA gene next generation sequencing

N Sun, Y Chen, J Zhang, J Cao, H Huang… - Frontiers in …, 2023 - frontiersin.org
Objectives This study aimed to identify the bacterial composition in the pancreatic fluid of
severe and critical acute pancreatitis (SAP and CAP) patients. Methods A total of 78 …

Mortality and costs related to severe acute pancreatitis in the intensive care units of Australia and New Zealand (ANZ), 2003–2020

SG Barreto, B Kaambwa, K Venkatesh, SC Sasson… - Pancreatology, 2023 - Elsevier
Background and objective Comprehensive data on the burden of severe acute pancreatitis
(SAP) in global intensive care units (ICUs) and trends over time are lacking. Our objective …

Acute pancreatitis is characterized by generalized intestinal barrier dysfunction in early stage

S Agarwal, P Goswami, S Poudel, D Gunjan, N Singh… - Pancreatology, 2023 - Elsevier
Background and aims The role of intestinal-barrier in acute pancreatitis (AP) is poorly
understood. We aimed to assess structural and functional changes in the intestinal-barrier in …

Acute pancreatitis: Current clinical approaches, molecular pathophysiology, and potential therapeutics

MB Wiley, K Mehrotra, J Bauer, C Yazici… - Pancreas, 2023 - journals.lww.com
Objective Severe acute pancreatitis (SAP), pancreatic inflammation leading to multiorgan
failure, is associated with high morbidity and mortality. There is a critical need to identify …

Prognostic significance of organ failure and infected pancreatic necrosis in acute pancreatitis: An updated systematic review and meta‐analysis

WM Hu, TR Hua, YL Zhang, GR Chen… - Journal of Digestive …, 2023 - Wiley Online Library
Objectives In patients with acute pancreatitis (AP), minimally invasive treatment and the step‐
up approach have been widely used to deal with infected pancreatic necrosis (IPN) in the …