Mesenchymal stromal cells (MSCs) have been extensively tested for the treatment of
numerous clinical conditions and have demonstrated good safety but mixed efficacy …

Fractures are the most common large organ trauma in humans. The initial inflammatory
response promotes bone healing during the initial post-fracture phase, but chronic and …

Articular cartilage injury is common in various conditions, including osteoarthritis, rheumatic
diseases, and trauma. Current treatments for cartilage injury fail to completely regenerate …

The immunosuppressive non-classical human leukocyte antigen-G (HLA-G) can elicits pro-
viral activities by down-modulating immune responses. We analysed soluble forms of HLA …

Kidney transplantation is a lifesaving procedure for patients with end-stage kidney disease
(ESKD). Organs derived from donation after cardiac death (DCD) are constantly increasing; …

Mesenchymal stem/stromal cells (MSCs) are known as multipotent cells due to their ability to
differentiate into various cell lineages of mesoderm origin. Recent developments in stem cell …

Fractures are the most common large organ trauma in humans. The initial inflammatory re-
sponse promotes bone healing during the initial post-fracture phase, but chronic and …

The tumor stroma is now recognized as a key factor in cancer development, as is the need
for a deeper understanding of the underlying mechanisms for improving therapies for this …

During kidney transplant procedure transplanted organs can undergo ischaemia reperfusion
phenomena, often associated with the onset of acute kidney damage, loss of kidney function …

The disclosure provides means of treating autoimmunity through reprogramming of antigen
presenting cells in an individual in need of treatment through administration of fibroblasts …