Nutritional and metabolic factors in amyotrophic lateral sclerosis

A Ludolph, L Dupuis, E Kasarskis, F Steyn… - Nature Reviews …, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …

Evidence of metabolic dysfunction in amyotrophic lateral sclerosis (ALS) patients and animal models

K Maksimovic, M Youssef, J You, HK Sung, J Park - Biomolecules, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects motor
neurons, leading to muscle weakness, paralysis, and eventual death. Research from the …

Abnormal energy metabolism in ALS: a key player?

T Burg, L Van Den Bosch - Current opinion in neurology, 2023 - journals.lww.com
Abnormal energy metabolism in ALS: a key player? : Current Opinion in Neurology
Abnormal energy metabolism in ALS: a key player? : Current Opinion in Neurology Log in …

[HTML][HTML] Distinct hypothalamic involvement in the amyotrophic lateral sclerosis-frontotemporal dementia spectrum

NY Tse, M Bocchetta, EG Todd, EM Devenney, S Tu… - NeuroImage: Clinical, 2023 - Elsevier
Background Hypothalamic dysregulation plays an established role in eating abnormalities in
behavioural variant frontotemporal dementia (bvFTD) and amyotrophic lateral sclerosis …

Plasma oxylipin profiling by high resolution mass spectrometry reveal signatures of inflammation and hypermetabolism in amyotrophic lateral sclerosis

AB Chaves-Filho, LS Diniz, RS Santos, RS Lima… - Free Radical Biology …, 2023 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by
progressive loss of motor neurons, systemic hypermetabolism, and inflammation. In this …

Why is nutrition vital for advancing ALS care and clinical research?

EJ Kasarskis, R Tandan - Amyotrophic Lateral Sclerosis and …, 2023 - Taylor & Francis
Objective: We endeavor to draw attention to what appears to be a gap in the management of
ALS patients and the potential uncertainty of clinical drug trial research results in the …

Enteral tube feeding for amyotrophic lateral sclerosis/motor neuron disease

ME Freitas, B Ritsma, L Zinman - Cochrane Database of …, 2023 - cochranelibrary.com
Background Maintaining adequate nutrition is critical for people with amyotrophic lateral
sclerosis (ALS), also known as motor neuron disease (MND). Enteral tube feeding is offered …

Insulin in amyotrophic lateral sclerosis: impairment, tests and treatment

A Rappoport - 2023 - preprints.org
Background. Amyotrophic Lateral Sclerosis (ALS) is a devastating disease involving motor
neuron degeneration. The few drugs approved for treatment have at most a marginal benefit …