Hybrid immunity to SARS-CoV-2 from infection and vaccination—evidence synthesis and implications for new COVID-19 vaccines

JR Spinardi, A Srivastava - Biomedicines, 2023 - mdpi.com
COVID-19 has taken a severe toll on the global population through infections,
hospitalizations, and deaths. Elucidating SARS-CoV-2 infection-derived immunity has led to …

Modified SEIAR infectious disease model for Omicron variants spread dynamics

F Cao, X Lü, YX Zhou, XY Cheng - Nonlinear Dynamics, 2023 - Springer
The highly infectious and low-mortality Omicron variant of COVID-19 was identified in
Botswana and reported to the WHO by South Africa. Spread dynamics is often used in the …

Improvement of mucosal immunity by a live-attenuated SARS-CoV-2 nasal vaccine

J Yeung, T Wang, PY Shi - Current Opinion in Virology, 2023 - Elsevier
Highlights•Several intranasal SARS-CoV-2 vaccines are now in use and induce mucosal
immunity.•Live-attenuated SARS-CoV-2 as nasal vaccines would induce hybrid …

Changing severity and epidemiology of adults hospitalized with coronavirus disease 2019 (COVID-19) in the United States after introduction of COVID-19 vaccines …

N Kojima, K Adams, WH Self, M Gaglani… - Clinical Infectious …, 2023 - academic.oup.com
Introduction Understanding the changing epidemiology of adults hospitalized with
coronavirus disease 2019 (COVID-19) informs research priorities and public health policies …

In SARS-CoV-2 delta variants, Spike-P681R and D950N promote membrane fusion, Spike-P681R enhances spike cleavage, but neither substitution affects …

Y Furusawa, M Kiso, S Iida, R Uraki, Y Hirata, M Imai… - …, 2023 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2 lineage) variant was first
identified at the end of 2020 and possessed two unique amino acid substitutions in its spike …

A spike-trimer protein-based tetravalent COVID-19 vaccine elicits enhanced breadth of neutralization against SARS-CoV-2 Omicron subvariants and other variants

R Wang, H Huang, C Yu, C Sun, J Ma, D Kong… - Science China Life …, 2023 - Springer
Multivalent vaccines combining crucial mutations from phylogenetically divergent variants
could be an effective approach to defend against existing and future SARS-CoV-2 variants …

Affinity exploration of SARS-CoV-2 RBD variants to mAb-functionalized plasmonic metasurfaces for label-free immunoassay boosting

F Li, J Hong, C Guan, K Chen, Y Xie, Q Wu, J Chen… - ACS …, 2023 - ACS Publications
Plasmonic metasurfaces (PMs) functionalized with the monoclonal antibody (mAb) are
promising biophotonic sensors for biomolecular interaction analysis and convenient …

A Mosaic Nanoparticle Vaccine Elicits Potent Mucosal Immune Response with Significant Cross‐Protection Activity against Multiple SARS‐CoV‐2 Sublineages

X Zhang, S Wu, J Liu, R Chen, Y Zhang, Y Lin… - Advanced …, 2023 - Wiley Online Library
Because of the rapid mutation and high airborne transmission of SARS‐CoV‐2, a universal
vaccine preventing the infection in the upper respiratory tract is particularly urgent. Here, a …

Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA. 1-BA. 5

Y Wang, A Yan, D Song, C Dong, M Rao, Y Gao, R Qi… - Cell Discovery, 2023 - nature.com
SARS-CoV-2 Omicron subvariants have demonstrated extensive evasion from monoclonal
antibodies (mAbs) developed for clinical use, which raises an urgent need to develop new …

Durable reprogramming of neutralizing antibody responses following Omicron breakthrough infection

WS Lee, HX Tan, A Reynaldi, R Esterbauer… - Science …, 2023 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection of
vaccinated individuals is increasingly common with the circulation of highly immune evasive …