Nonsense-mediated mRNA decay factor functions in human health and disease
L Sun, J Mailliot, C Schaffitzel - Biomedicines, 2023 - mdpi.com
Nonsense-mediated mRNA decay (NMD) is a cellular surveillance mechanism that
degrades mRNAs with a premature stop codon, avoiding the synthesis of C-terminally …
degrades mRNAs with a premature stop codon, avoiding the synthesis of C-terminally …
Nonsense-mediated mRNA decay: Mechanistic insights and physiological significance
I Patro, A Sahoo, BR Nayak, R Das, S Majumder… - Molecular …, 2023 - Springer
Nonsense-mediated mRNA decay (NMD) is an evolutionarily conserved surveillance
mechanism across eukaryotes and also regulates the expression of physiological …
mechanism across eukaryotes and also regulates the expression of physiological …
Nonsense-mediated decay machinery in Plasmodium falciparum is inefficient and non-essential
Nonsense-mediated decay (NMD) is a conserved mRNA quality control process that
eliminates transcripts bearing a premature termination codon. In addition to its role in …
eliminates transcripts bearing a premature termination codon. In addition to its role in …
Structural systems biology approach delineate the functional implications of SNPs in exon junction complex interaction network
DD VM, V Sivaramakrishnan… - Journal of Biomolecular …, 2023 - Taylor & Francis
In eukaryotes, transcripts that carry premature termination codons (PTC) leading to truncated
proteins are degraded by the Nonsense Mediated Decay (NMD) machinery. Missense and …
proteins are degraded by the Nonsense Mediated Decay (NMD) machinery. Missense and …
UPF3A is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cells
C Chen, Y Shen, L Li, Y Ren… - Life Science …, 2023 - life-science-alliance.org
Nonsense-mediated mRNA decay (NMD) is a highly conserved regulatory mechanism of
post-transcriptional gene expression in eukaryotic cells. NMD plays essential roles in mRNA …
post-transcriptional gene expression in eukaryotic cells. NMD plays essential roles in mRNA …
UPF3A is a ubiquitously expressed NMD factor among mouse tissues
X Ma, Y Li, C Chen, T Li - bioRxiv, 2023 - biorxiv.org
Nonsense-mediated mRNA decay (NMD), an important post-transcriptional regulatory
mechanism in gene expression, is actively involved in a series of cellular and physiological …
mechanism in gene expression, is actively involved in a series of cellular and physiological …
[HTML][HTML] Deficiência intelectual com herança ligada ao X: estudo de irmandades com dois ou mais indivíduos afetados selecionadas pelos desvios extremos do …
MD Hanna - 2023 - bdtd.ibict.br
A deficiência intelectual (DI) é definida por limitações da função intelectual e do
comportamento adaptativo presente antes dos 22 anos de idade e afeta aproximadamente …
comportamento adaptativo presente antes dos 22 anos de idade e afeta aproximadamente …
[图书][B] Simplified nonsense: New methods for interrogating NMD
H Alalam - 2023 - gupea.ub.gu.se
Nonsense mediated decay (NMD) is a pathway that regulates RNA turnover. Since its
discovery, this pathway has been implicated in a variety of cellular processes ranging from …
discovery, this pathway has been implicated in a variety of cellular processes ranging from …
mRNA sequence features determine the efficiency of translation termination and association of the nonsense-mediated mRNA decay machinery with elongating …
K Mangkalaphiban - 2023 - repository.escholarship.umassmed …
Translation of mRNA into protein is terminated when the ribosome encounters one of the
three stop codons (UAA, UAG, and UGA) at the end of an open reading frame (ORF) …
three stop codons (UAA, UAG, and UGA) at the end of an open reading frame (ORF) …