PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma
F Brown-Burke, I Hwang, S Sloan… - Blood …, 2023 - ashpublications.org
Mantle cell lymphoma (MCL) is an incurable B-cell malignancy that comprises up to 6% of
non-Hodgkin lymphomas diagnosed annually and is associated with a poor prognosis. The …
non-Hodgkin lymphomas diagnosed annually and is associated with a poor prognosis. The …
Prenatal social support in low-risk pregnancy shapes placental epigenome
Background Poor social support during pregnancy has been linked to inflammation and
adverse pregnancy and childhood health outcomes. Placental epigenetic alterations may …
adverse pregnancy and childhood health outcomes. Placental epigenetic alterations may …
Memory phase-specific genes in the Mushroom Bodies identified using CrebB-target DamID
N Sgammeglia, YF Widmer, JC Kaldun, C Fritsch… - PLoS …, 2023 - journals.plos.org
The formation of long-term memories requires changes in the transcriptional program and
de novo protein synthesis. One of the critical regulators for long-term memory (LTM) …
de novo protein synthesis. One of the critical regulators for long-term memory (LTM) …
Multi-omic analysis of CIC's functional networks reveals novel interaction partners and a potential role in mitotic fidelity
Y Takemon, VG LeBlanc, J Song, SY Chan, SD Lee… - Cancers, 2023 - mdpi.com
Simple Summary Capicua (CIC) is a gene that is frequently mutated in several cancer types,
including stomach cancers and certain subtypes of brain tumours and sarcomas. CIC, the …
including stomach cancers and certain subtypes of brain tumours and sarcomas. CIC, the …
[PDF][PDF] Multi-Omic Analysis of CIC's Functional Networks Reveals Novel Interaction Partners and a Potential Role in Mitotic Fidelity. Cancers 2023, 15, 2805
Y Takemon, VG LeBlanc, J Song, SY Chan, SD Lee… - 2023 - open.library.ubc.ca
CIC encodes a transcriptional repressor and MAPK signalling effector that is inactivated by
loss-of-function mutations in several cancer types, consistent with a role as a tumour …
loss-of-function mutations in several cancer types, consistent with a role as a tumour …
Advances in Preclinical Mantle Cell Lymphoma Research: A Novel Combination Regimen and a Novel Mouse Model
FD Brown - 2023 - rave.ohiolink.edu
Abstract Mantle Cell Lymphoma (MCL) is a B cell lymphoma distinguished from other B cell
lymphomas by at (11; 14)(q13: q32) translocation juxtaposing the CCND1 gene downstream …
lymphomas by at (11; 14)(q13: q32) translocation juxtaposing the CCND1 gene downstream …
The role of capicua in adult hippocampal neurogenesis
B Hourigan - 2023 - era.library.ualberta.ca
Adult hippocampal neurogenesis (AHN) involves generating hippocampal granule neurons
and the subsequent integration of granule neurons into the hippocampus synaptic circuit …
and the subsequent integration of granule neurons into the hippocampus synaptic circuit …