[HTML][HTML] Evidence of shared genetic factors in the etiology of gastrointestinal disorders and endometriosis and clinical implications for disease management

F Yang, Y Wu, R Hockey, J Doust, GD Mishra… - Cell Reports …, 2023 - cell.com
In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often
observed. Using large-scale datasets, we report a genetic correlation between …

Functional genomics of reproduction in pigs: Are we there yet?

DJ Nonneman, CA Lents - Molecular Reproduction and …, 2023 - Wiley Online Library
Reproductive failure is the main reason for culling females in swine herds and is both a
financial and sustainability issue. Because reproductive traits are complex and lowly to …

A Novel Perspective on Neuronal Control of Anatomical Patterning, Remodeling, and Maintenance

E Jones, KA McLaughlin - International Journal of Molecular Sciences, 2023 - mdpi.com
While the nervous system may be best known as the sensory communication center of an
organism, recent research has revealed a myriad of multifaceted roles for both the CNS and …

[HTML][HTML] Serum 25-hydroxyvitamin D levels and the risk of idiopathic central precocious puberty in girls

DM Gan, J Fang, PP Zhang, YD Zhao, YN Xu - Clinics, 2023 - SciELO Brasil
Highlights Insufficient vitamin D levels and sufficient vitamin D levels had a lower risk of
ICPP. The vitamin D levels in ICPP girls could affect by height, weight, breast stage, mother's …

Genome-wide association study of age at menarche in the Taiwan Biobank suggests NOL4 as a novel associated gene

MC Tsai, CH Hsu, SK Chu, MH Roy-Gagnon… - Journal of Human …, 2023 - nature.com
Sexual maturation is a complex physiological process that involves multiple variables, such
as genetic and environmental factors. Among females, age at menarche (AM) is a critical …

Metabolically favorable adiposity and bone mineral density: a Mendelian randomization analysis

VL Bland, JW Bea, SB Going, H Yaghootkar, A Arora… - …, 2023 - Wiley Online Library
Objective This analysis assessed the putative causal association between genetically
predicted percent body fat and areal bone mineral density (aBMD) and, more specifically …

The Effect of Secondary Sexual Characteristics Outset Time Abnormality on Addiction in Adults: a Mendelian Randomization Study

C Pan, C Li, S Cheng, Y Chen, J Zhang… - International Journal of …, 2023 - Springer
The abnormal timing of pubertal development is a risk factor for addictive disorders among
adolescents. However, whether the precocious or late puberty has influence on addiction in …

mTOR pathway candidate genes and obesity interaction on breast cancer risk in black women from the Women's Circle of Health Study

MN Ilozumba, L Yaghjyan, S Datta, J Zhao… - Cancer Causes & …, 2023 - Springer
Background Obesity is known to stimulate the mammalian target of rapamycin (mTOR)
signaling pathway and both obesity and the mTOR signaling pathway are implicated in …

Chromosomal polymorphisms and susceptibility to menstrual disorders: a retrospective analysis of 24,578 women

C Ran, L Xiaoyan, Z Wenjie, Z Xiaoyang, N Ying… - Archives of Gynecology …, 2023 - Springer
Purpose To evaluate the association between the polymorphic variants of chromosomes
and menstrual disorders. Methods The data from our previous retrospective, single-center …

mTOR pathway candidate genes and energy intake interaction on breast cancer risk in Black women from the Women's Circle of Health Study

MN Ilozumba, L Yaghjyan, S Datta, J Zhao… - European Journal of …, 2023 - Springer
Background Excessive energy intake has been shown to affect the mammalian target of the
rapamycin (mTOR) signaling pathway and breast cancer risk. It is not well understood …