Interaction of SARS-CoV-2 with host cells and antibodies: experiment and simulation

H Nguyen, HL Nguyen, PD Lan, NQ Thai… - Chemical Society …, 2023 - pubs.rsc.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …

Research progress in spike mutations of SARS‐CoV‐2 variants and vaccine development

X He, C He, W Hong, J Yang… - Medicinal Research …, 2023 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) pandemic can hardly end with the
emergence of different variants over time. In the past 2 years, several variants of severe …

Uncovering the morphological differences between SARS-CoV-2 and SARS-CoV based on transmission electron microscopy images

BA Taha, Y Al Mashhadany, Q Al-Jubouri… - Microbes and …, 2023 - Elsevier
Comprehending the morphological disparities between SARS-CoV-2 and SARS-CoV
viruses can shed light on the underlying mechanisms of infection and facilitate the …

Genomic surveillance of SARS‐CoV‐2 strains circulating in Iran during six waves of the pandemic

K Sadeghi, S Zadheidar, A Zebardast… - Influenza and Other …, 2023 - Wiley Online Library
Background SARS‐CoV‐2 genomic surveillance is necessary for the detection, monitoring,
and evaluation of virus variants, which can have increased transmissibility, disease severity …

SARS-CoV-2 vaccine breakthrough infections (VBI) by Omicron variant (B. 1.1. 529) and consequences in structural and functional impact

Z Abduljaleel, S Melebari, M Athar, S Dehlawi… - Cellular …, 2023 - Elsevier
This study investigated the efficacy of existing vaccines against hospitalization and infection
due to the Omicron variant of COVID-19, particularly for those who received two doses of …

[HTML][HTML] Drug repurposing for the treatment of COVID-19: Targeting nafamostat to the lungs by a liposomal delivery system

P Reus, H Guthmann, N Uhlig, M Agbaria… - Journal of Controlled …, 2023 - Elsevier
Despite tremendous global efforts since the beginning of the COVID-19 pandemic, still only
a limited number of prophylactic and therapeutic options are available. Although vaccination …

A Comprehensive Analysis of Structural and Functional Changes Induced by SARS-CoV-2 Spike Protein Mutations

AGA Mushebenge, SC Ugbaja, NA Mbatha, RB Khan… - COVID, 2023 - mdpi.com
The emergence of SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has
sparked intense research on its spike protein, which is essential for viral entrance into host …

Molecular evolution and structural analyses of the spike glycoprotein from Brazilian SARS-CoV-2 genomes: the impact of selected mutations

PA Gröhs Ferrareze, RA Zimerman… - Journal of …, 2023 - Taylor & Francis
The COVID-19 pandemic caused by SARS-CoV-2 has reached by February 2022 more than
380 million cases and 5.5 million deaths worldwide since its beginning in late 2019, leading …

Molecular epidemiology of SARS-CoV-2 during five COVID-19 waves and the significance of low-frequency lineages

K Subramoney, N Mtileni, J Giandhari, Y Naidoo… - Viruses, 2023 - mdpi.com
SARS-CoV-2 lineages and variants of concern (VOC) have gained more efficient
transmission and immune evasion properties with time. We describe the circulation of VOCs …

Insights on the interaction of SARS-CoV-2 variant B. 1.617. 2 with antibody CR3022 and analysis of antibody resistance

S Ks, AS Nair - Journal of Genetic Engineering and Biotechnology, 2023 - Springer
Background The existence of mutated Delta (B. 1.617. 2) variants of SARS-CoV-2 causes
rapid transmissibility, increase in virulence, and decrease in the effectiveness of public …